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Expert Review of Gastroenterology & Hepatology, 2023
Introduction Biliary atresia is a potentially fatal condition of the bile ducts – both intra- and extrahepatic, for which we have no cure. Though principally a cholestatic condition, much of its pathology stems from its tendency to aggressively induce ...
M. Davenport, R. Kronfli, Erica Makin
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Introduction Biliary atresia is a potentially fatal condition of the bile ducts – both intra- and extrahepatic, for which we have no cure. Though principally a cholestatic condition, much of its pathology stems from its tendency to aggressively induce ...
M. Davenport, R. Kronfli, Erica Makin
semanticscholar +1 more source
Serum matrix metalloproteinase‐7 in biliary atresia: A Japanese multicenter study
Hepatology Research, 2022Biliary atresia (BA) is among the commonest indications for liver transplantation (LT) in children. We examined whether serum matrix metalloproteinase‐7 (MMP‐7) is useful for diagnosis of BA in Japanese infants, and whether serum MMP‐7 concentrations ...
H. Sakaguchi +16 more
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Update on etiology and pathogenesis of biliary atresia.
Current pediatric reviews, 2022Biliary atresia is a rare inflammatory sclerosing obstructive cholangiopathy that initiates in infancy as complete choledochal blockage and progresses to the involvement of intrahepatic biliary epithelium.
Patrícia Quelhas +2 more
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Seminars in Neonatology, 2003
Biliary atresia (BA) is a congenital obliterative cholangiopathy of unknown aetiology, affecting both the intra- and extrahepatic bile ducts. Although relatively rare, BA must be excluded in any infant with conjugated hyperbilirubinaemia since the prognosis is improved by early diagnosis and prompt surgery.
Hiroyuki, Kobayashi, Mark D, Stringer
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Biliary atresia (BA) is a congenital obliterative cholangiopathy of unknown aetiology, affecting both the intra- and extrahepatic bile ducts. Although relatively rare, BA must be excluded in any infant with conjugated hyperbilirubinaemia since the prognosis is improved by early diagnosis and prompt surgery.
Hiroyuki, Kobayashi, Mark D, Stringer
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Pediatrics In Review, 1989
Biliary atresia is a pathologic entity in which there is obliteration of some portion of the extrahepatic bile ducts. In the past, occlusion of the proximal ducts (at the liver hilus) was referred to as "noncorrectable" (Fig 1). If only the distal duct is occluded (and the proximal duct is patent), the lesion was referred to as "correctable." The ...
E A, Wanek +3 more
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Biliary atresia is a pathologic entity in which there is obliteration of some portion of the extrahepatic bile ducts. In the past, occlusion of the proximal ducts (at the liver hilus) was referred to as "noncorrectable" (Fig 1). If only the distal duct is occluded (and the proximal duct is patent), the lesion was referred to as "correctable." The ...
E A, Wanek +3 more
openaire +5 more sources
The Lancet, 2009
Biliary atresia is a rare disease of infancy, which has changed within 30 years from being fatal to being a disorder for which effective palliative surgery or curative liver transplantation, or both, are available. Good outcomes for infants depend on early referral and timely Kasai portoenterostomy, and thus a high index of suspicion is needed for ...
Jane L, Hartley +2 more
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Biliary atresia is a rare disease of infancy, which has changed within 30 years from being fatal to being a disorder for which effective palliative surgery or curative liver transplantation, or both, are available. Good outcomes for infants depend on early referral and timely Kasai portoenterostomy, and thus a high index of suspicion is needed for ...
Jane L, Hartley +2 more
openaire +5 more sources
2021
Biliary Atresia (BA) affects approximately 1:20,000 babies and is the most frequent cause of surgical jaundice in children. BA presents in the first few weeks of life with pale stools and dark urine in otherwise healthy infants. It is the end result of a destructive inflammatory process of the bile ducts, with unclear origins.
Betalli P., Cheli M., D'Antiga L.
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Biliary Atresia (BA) affects approximately 1:20,000 babies and is the most frequent cause of surgical jaundice in children. BA presents in the first few weeks of life with pale stools and dark urine in otherwise healthy infants. It is the end result of a destructive inflammatory process of the bile ducts, with unclear origins.
Betalli P., Cheli M., D'Antiga L.
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Current Opinion in Pediatrics, 1997
Biliary atresia, a progressive obliterative process involving the bile ducts, has its onset in the newborn period. It is characterized by worsening cholestasis, hepatic fibrosis, and cirrhosis, which lead to portal hypertension and a decline in hepatic synthetic function. Untreated, the outcome is uniformly fatal.
W, Middlesworth, R P, Altman
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Biliary atresia, a progressive obliterative process involving the bile ducts, has its onset in the newborn period. It is characterized by worsening cholestasis, hepatic fibrosis, and cirrhosis, which lead to portal hypertension and a decline in hepatic synthetic function. Untreated, the outcome is uniformly fatal.
W, Middlesworth, R P, Altman
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Journal of hepato-biliary-pancreatic sciences, 2021
The biliary atresia (BA) inflammatory process leads to various obstructive patterns of extrahepatic biliary trees. The significance of the various BA obstructive patterns is unclear.
H. Sasaki +7 more
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The biliary atresia (BA) inflammatory process leads to various obstructive patterns of extrahepatic biliary trees. The significance of the various BA obstructive patterns is unclear.
H. Sasaki +7 more
semanticscholar +1 more source