Results 161 to 170 of about 575,936 (265)

Multi‐omics–driven precision medicine

iMeta, EarlyView.
Multi‐omics‐driven precision medicine (MODPM) provides a multiscale, continuously learnable framework that integrates genomics, epigenomics, transcriptomics, proteomics, metabolomics, microbiome profiles, and clinical data. Powered by artificial intelligence and foundation models, MODPM enables cross‐modal representation learning, contextual modeling ...
Huibo Li, Zhe Zhao, Yifan Zhang, Yao Ma, Gaofei Hu, Min Zeng, Zhanqun Yang, Zixuan Zhao, Xin Zhou, Wei Hu, Yuxuan Sun, Meng Su, Jun Li, Matthew Whiteman, Wei Fu, Chao Zhong, Lemin Zheng, Long Chen, Hairong Lv, Rongsheng Zhao, Yi Zhun Zhu   +20 more
wiley   +1 more source

Rethinking early recurrence in gallbladder cancer: Why one cutoff does not fit all stages

Current Problems in Surgery
Ya-Fei Hu, MD, PhD, Fei Liu, MD, PhD, Wen-Jie Ma, MD, PhD, Jun-Ke Wang, MD, PhD, Hai-Jie Hu, MD, PhD, Yan-Wen Jin, MD, PhD, Fu-Yu Li, MD, PhD   +6 more
doaj   +1 more source

Economic Evidence on Biliary Tract Cancer: A Systematic Review. [PDF]

Cancers (Basel)
Rocha-Gomes J, Teixeira AS, Ruiz-Romeo M, Oliveira JM, Ramos P.   +4 more
europepmc   +1 more source

High‐Sugar Diet and Intestinal Diseases: A Shared Microbiota–Barrier–Immunity–Metabolism Axis in Inflammatory Bowel Disease, Food Allergy, and Colorectal Cancer

iNew Medicine, EarlyView.
ABSTRACT The global incidence of intestinal diseases—including food allergy, inflammatory bowel disease (IBD), and colorectal cancer (CRC)—continues to escalate in parallel with the expansion of the “Western diet,” within which the high‐sugar diet (HSD) has emerged as a pivotal yet under‐recognized dietary driver.
Yuchen Wang, Yajuan Wu, Huayang Sheng, Shouhong Jiang, Jinping Cheng, Ye Kuang, Miao Liu, Lei Feng, Yanan Sun, Jinzhi Duan   +9 more
wiley   +1 more source

Research Progress of Berberine in Kidney Disease: Targeting Mitochondria and Ferroptosis

iNew Medicine, EarlyView.
This figure illustrates the model‐specific renoprotective mechanisms of berberine (BBR) across three major kidney diseases. From left to right, the diagram shows that BBR targets distinct core pathways depending on the pathological context: in diabetic nephropathy (DN), BBR activates AMPK to improve mitochondrial energy metabolism; in acute kidney ...
Liuqing Wang, Rongyu Guo, Xiaojun Feng, Liqin Tang   +3 more
wiley   +1 more source

The expression and related biological behavior of the anillin-actin-binding-protein gene in hepatocellular-carcinoma cells

Asian Journal of Surgery, 2023
Di Zhang, Hui Jiao Zhang, Guo Sheng Wang, Jian Guo Li   +3 more
doaj   +1 more source

Exposure–Recovery Approach for Hepatic Toxicity Analysis of Pyrethroid Lambda‐Cyhalothrin: Histopathological, Histochemical, and Biochemical Responses in Oreochromis niloticus

Journal of Applied Toxicology, EarlyView.
ABSTRACT Lambda‐cyhalothrin is a synthetic pyrethroid insecticide widely used in agriculture, but its potential to contaminate aquatic ecosystems and exert high toxicity on fish at low concentrations raises ecotoxicological concerns. While standard histopathological and biochemical assessments are common, the novel integration of pigment‐based ...
Carlos Eurico Fernandes, André Luiz do Nascimento Silva, Tiago Venancio da Silva, Karine Nathiele Nogueira Farias, Sabrina Fuzer Gonçalves, Brenda de Oliveira Martins, Maria Eduarda Corona Garcia, Lilian Franco‐Belussi   +7 more
wiley   +1 more source

Integrated Multi-Omics Profiling Identifies PDZ-Binding Kinase (PBK) as a Novel Prognostic Biomarker in Hepatocellular Carcinoma

Journal of Hepatocellular Carcinoma
Juan Zhang,1,* Yingyu Xu,2,* Xiaojian Ni,2,* Zhiyi Mao,3,* Haitao Xiao,4 Maopei Chen,1 Youpei Lin,5 Jiaomeng Pan,5 Boheng Zhang,6 Lan Zhang,1 Xueying Zheng,3 Guohe Song,5 Ningling Ge1 1Department of Hepatobiliary Oncology,
Zhang J, Xu Y, Ni X, Mao Z, Xiao H, Chen M, Lin Y, Pan J, Zhang B, Zhang L, Zheng X, Song G, Ge N   +12 more
doaj  

Comprehensive Genomic Profiles of Patients With Biliary Tract Cancer. [PDF]

Cancer Med
Yang X, Zhu T, Hu X, Jiang Z, Jin H.
europepmc   +1 more source

Histological Analysis of Cryopreserved Venous Allografts Used for Liver Transplantation and Hepato‐Biliary‐Pancreatic Surgery

Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Background Cryopreserved venous allografts, which we pioneered in 1999 for use in living donor liver transplantation and hepato‐biliary‐pancreatic surgery, are widely used and are believed to preserve vascular architecture with minimal anticoagulation or immunosuppression requirements and patency comparable to autologous grafts.
Yusuke Seki, Akihiko Ichida, Sumihito Tamura, Mariko Tanaka, Yoshinori Inagaki, Kyoji Ito, Rihito Nagata, Takuya Hashimoto, Nobuhisa Akamatsu, Tetsuo Ushiku, Kiyoshi Hasegawa   +10 more
wiley   +1 more source