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The Lancet, 2021 Biliary tract cancers, including intrahepatic, perihilar, and distal cholangiocarcinoma as well as gallbladder cancer, are low-incidence malignancies in most high-income countries, but represent a major health problem in endemic areas; moreover, the incidence of intrahepatic cholangiocarcinoma is rising globally. Surgery is the cornerstone of cure; the
R. Katie Kelley +5 more
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Durvalumab plus Gemcitabine and Cisplatin in Advanced Biliary Tract Cancer.
NEJM Evidence, 2022Durvalumab Combination for Biliary Tract CancerThis trial randomly assigned patients with previously untreated locally advanced or metastatic biliary tract cancer to receive durvalumab or placebo in combination with gemcitabine plus cisplatin.
D. Oh +28 more
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Hepatology, 2023
Background and Aims: We examined gallbladder and biliary tract mortality predictors in the US National Health and Nutrition Examination Survey (NHANES), 1988-1994, with 31 years of linked mortality data, and gallstone disease prevalence trends and ...
A. Unalp-arida, C. Ruhl
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Background and Aims: We examined gallbladder and biliary tract mortality predictors in the US National Health and Nutrition Examination Survey (NHANES), 1988-1994, with 31 years of linked mortality data, and gallstone disease prevalence trends and ...
A. Unalp-arida, C. Ruhl
semanticscholar +1 more source
Pitfalls, challenges, and updates in adjuvant systemic treatment for resected biliary tract cancer
Expert Review of Gastroenterology & Hepatology, 2021Introduction: Unfortunately, potentially curative surgical resection is possible in approximately the 25% of biliary tract cancer (BTC) patients at diagnosis, and even following radical surgery, relapse rates remain high.
A. Rizzo, G. Brandi
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Hepatology, 2021
Biliary tract cancer (BTC) exhibits diverse molecular characteristics. However, reliable biomarkers that predict therapeutic responses are yet to be discovered.
Jihoon G. Yoon +12 more
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Biliary tract cancer (BTC) exhibits diverse molecular characteristics. However, reliable biomarkers that predict therapeutic responses are yet to be discovered.
Jihoon G. Yoon +12 more
semanticscholar +1 more source
New England Journal of Medicine, 1956
Stenosis of the Sphincter of Oddi The validity of the concept that stenosis of the sphincter of Oddi contributes to biliary-tract symptoms is gradually gaining support. It is being recognized with increasing frequency as a pathologic fact both at the time of initial cholecystectomy and as a cause of continued or recurrent symptoms in some patients ...
Richard B. Cattell, Kenneth W. Warren
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Stenosis of the Sphincter of Oddi The validity of the concept that stenosis of the sphincter of Oddi contributes to biliary-tract symptoms is gradually gaining support. It is being recognized with increasing frequency as a pathologic fact both at the time of initial cholecystectomy and as a cause of continued or recurrent symptoms in some patients ...
Richard B. Cattell, Kenneth W. Warren
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Current Opinion in Gastroenterology, 1999
Cholangiocytes, the cells lining the bile ducts, are now recognized as important contributors to and modulators of bile formation. During the last few years, remarkable insights have been made into the mechanisms of fluid, electrolyte, and solute transport by biliary epithelia, as well as increasing knowledge of the complex endocrine, paracrine, and ...
Richard T. Prall, Nicholas F. LaRusso
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Cholangiocytes, the cells lining the bile ducts, are now recognized as important contributors to and modulators of bile formation. During the last few years, remarkable insights have been made into the mechanisms of fluid, electrolyte, and solute transport by biliary epithelia, as well as increasing knowledge of the complex endocrine, paracrine, and ...
Richard T. Prall, Nicholas F. LaRusso
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Recent advances of immunotherapy for biliary tract cancer
Expert Review of Gastroenterology & Hepatology, 2020Introduction: Biliary tract cancer (BTC) is a heterogeneous group of aggressive malignancies comprising intrahepatic cholangiocarcinoma, extrahepatic cholangiocarcinoma, gallbladder cancer, and ampulla of Vater cancer.
A. Rizzo, A. Ricci, G. Brandi
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