Results 81 to 90 of about 83,082 (294)

Prescription drug use in breastfeeding mothers and infant exposure: A register‐based cohort study

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Breast milk is the optimal infant nutrition; however, many infants may be exposed to prescription drugs if used by their mothers during breastfeeding. The aim of this study was to evaluate the prevalence and patterns of prescription drug use among breastfeeding mothers and to assess the availability of relative infant dose information for
Ditte Resendal Gotfredsen, Ida M. Heerfordt, Christoffer Storm Baden, Henrik Horwitz, Christina Gade, Jon Trærup Andersen   +5 more
wiley   +1 more source

OBSERVATIONS ON THE PLASMA PROTHROMBIN AND THE EFFECTS OF VITAMIN K IN PATIENTS WITH LIVER OR BILIARY TRACT DISEASE 1 [PDF]

, 1940
Frederick J. Pohle, John K. Stewart
openalex   +1 more source

Probability of pharmacokinetic/pharmacodynamic target attainment for different piperacillin/tazobactam dosing regimens in renally impaired patients in a non‐intensive care unit setting

British Journal of Clinical Pharmacology, EarlyView.
Aims To optimize antibiotic therapy for pathogens classified as susceptible, increased exposure (I), an increased exposure of piperacillin/tazobactam (PTZ) is required. However, dosing recommendations are currently only available for patients with normal renal function.
Emma Dohmann, Stefan Hagel, Max Kurlbaum, Paul Schellong, Oliver Scherf‐Clavel, Güzin Surat   +5 more
wiley   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

Prognostic role of inflammatory and tumor biomarkers in hilar cholangiocarcinoma patients receiving postoperative adjuvant therapy

Frontiers in Oncology
BackgroundHilar cholangiocarcinoma (HCCA) is an aggressive cancer with poor prognosis after surgery. The systemic immune-inflammation index (SII) has been proposed as a prognostic marker, but its relationship with other markers such as CA19-9 remains ...
Di Zeng, Di Zeng, Saud Ahmad Saad, Saud Ahmad Saad, Zhen You, Zhen You, Nansheng Cheng, Nansheng Cheng   +7 more
doaj   +1 more source

Exosomal MicroRNA signature acts as an efficient biomarker for non-invasive diagnosis of gallbladder carcinoma

iScience, 2022
Summary: Through a three-step study that relies on biomarker discovery, training, and validation, we identified a set of five exosomal microRNAs (miRNAs) that can be used to evaluate the risk of gallbladder carcinoma (GBC), including miR-552-3p, miR-581,
Pinghua Yang, Fengliang Song, Xinwei Yang, Xingzhou Yan, Xinyu Huang, Zhengjun Qiu, Zhijian Wen, Chi Liang, Xianglei Xin, Zhengqin Lei, Kecheng Zhang, Jue Yang, Hu Liu, Hongcheng Wang, Shijun Xiang, Liang Li, Baohua Zhang, Hongyang Wang   +17 more
doaj  

Trends in the utilization, expenditure and costs of noninsulin glucose‐lowering drugs in the Medicaid population: Steady increases in glucagon‐like peptide‐1 receptor agonist and sodium–glucose transporter‐2 inhibitor use, prices and expenditure

British Journal of Clinical Pharmacology, EarlyView.
Aims This study aimed to analyse changes in the utilization, expenditure and average cost of noninsulin glucose‐lowering drugs (GLDs) between 2008 and 2023. Methods This was a retrospective observational study of 2008–2023 data from the National Medicaid State Drug Utilization database.
Rawan O. Almadfaa
wiley   +1 more source

Artificial intelligence modelling of tyrosine kinase inhibitors at risk of malabsorption and bioavailability‐enhancing strategies

British Journal of Clinical Pharmacology, EarlyView.
Aims The study aims to predict and improve the absorption of tyrosine kinase inhibitors (TKIs) in patients with malabsorption issues, particularly those who have undergone bariatric surgery or are using proton‐pump inhibitors. The research involves 2 main components: the development of an artificial intelligence (AI) model to identify TKIs that are ...
Daan W. Huntjens, Olivier J. M. Béquignon, Stefanie D. Krens, Mark Löwenberg, Martine E. D. Chamuleau, Remco J. Molenaar, Anita M. G. Kramers, Marianne A. Kuijvenhoven, Imke H. Bartelink   +8 more
wiley   +1 more source

Global trends and epidemiological shifts in gastrointestinal cancers: insights from the past four decades

Cancer Communications, EarlyView.
Abstract Background The epidemiological profiles of gastrointestinal (GI) cancers vary across countries and over time, largely reflecting variations in risk factors and screening practices. We aimed to provide an overview of the current global burden of the five major types of GI cancers and conduct an updated evaluation of the long‐term trends of GI ...
Mengmeng Li, Sumei Cao, Rui‐Hua Xu
wiley   +1 more source

Combating cancer immunotherapy resistance: a nano‐medicine perspective

Cancer Communications, EarlyView.
Abstract Cancer immunotherapy offers renewed hope for treating this disease. However, cancer cells possess inherent mechanisms that enable them to circumvent each stage of the immune cycle, thereby evading anti‐cancer immunity and leading to resistance.
Xiangyi Kong, Xintong Xie, Juan Wu, Xiangyu Wang, Wenxiang Zhang, Shuowen Wang, Daria Valerievna Abbasova, Yi Fang, Hongnan Jiang, Jidong Gao, Jing Wang   +10 more
wiley   +1 more source