Results 151 to 160 of about 347,609 (391)
Abstract End‐ischemic viability testing by normothermic machine perfusion (NMP) represents an effective strategy to recover liver grafts having initially been discarded for liver transplantation (LT). However, its results in the setting of significant (≥30%) macrovesicular steatosis (MaS) have not been specifically assessed.
Damiano Patrono+8 more
wiley +1 more source
Gallbladder agenesis (GA) is a rare congenital anomaly of the biliary system often associated with other congenital abnormalities. Patients become symptomatic in 23% of cases.
Valeria Fiaschetti+4 more
doaj +1 more source
Trimebutine maleate in the treatment of functional biliary disorders: TRIBUNE study results
Introduction. The term «functional disorders of the biliary tract and bile ducts» defines the conditions, which produce typical patterns of biliary pains in the absence of obvious signs of organic lesions of the gallbladder and bile ducts.
V. T. Ivashkin+3 more
doaj +1 more source
Could the "SpyGlass Direct Visualization" System Open New Horizons for Treating Biliary Tract Diseases as a Percutaneous Cholangioscopy? [PDF]
Lee YS.
europepmc +1 more source
Pharmacokinetic Prediction and Cytotoxicity of New Quercetin Derivatives
ABSTRACT Quercetin (QUE) possesses various pharmacological properties; however, its low bioavailability and solubility hinder its beneficial effects. Enzymatic glycosylation has been explored to improve these aspects. In the present study, we used a sucrose phosphorylase variant to catalyze the regioselective transglucosylation of QUE, predicted the ...
Michele Goulart dos Santos+8 more
wiley +1 more source
Mass spectrometry in ocular drug research
Abstract Mass spectrometry (MS) has been proven as an excellent tool in ocular drug research allowing analyzes from small samples and low concentrations. This review begins with a short introduction to eye physiology and ocular pharmacokinetics and the relevance of advancing ophthalmic treatments.
Eva M. del Amo+6 more
wiley +1 more source
Surgical complications in human orthotopic liver transplantation. [PDF]
Between March 1, 1980 and December 31, 1984, 393 orthotopic liver transplantations (OLT) were performed in 313 consecutive recipients. Technical complications were responsible for a substantial morbidity (41/393 allograft loss--10.4%) and mortality (26 ...
Gordon, RD+3 more
core
Mammalian Tolerance to Amino Acid Heterochirality
Organisms use amino acids predominantly in l‐configuration. On the other hand, a series of studies show that a variety of d‐amino acids also occur in mammals and amino acid homochirality is not complete. Mammals de novo synthesize most amino acids with l‐configuration, but serine and aspartate are converted from l‐ to d‐configuration by endogenous ...
Jumpei Sasabe+4 more
wiley +1 more source
ClinBench-HPB: A Clinical Benchmark for Evaluating LLMs in Hepato-Pancreato-Biliary Diseases [PDF]
Hepato-pancreato-biliary (HPB) disorders represent a global public health challenge due to their high morbidity and mortality. Although large language models (LLMs) have shown promising performance in general medical question-answering tasks, the current evaluation benchmarks are mostly derived from standardized examinations or manually designed ...
arxiv
Nonlinear association structures in flexible Bayesian additive joint models [PDF]
Joint models of longitudinal and survival data have become an important tool for modeling associations between longitudinal biomarkers and event processes. The association between marker and log-hazard is assumed to be linear in existing shared random effects models, with this assumption usually remaining unchecked.
arxiv