Nanomedicine for Oral Delivery: Strategies to Overcome the Biological Barriers
Oral delivery is a preferred administration route for many clinical applications, valued for its strong patient compliance. In this review, how nanoparticles are engineered and deployed to overcome the gastrointestinal barriers that impede clinical translation of oral delivery formulations is examined.
Luke J. Kubiatowicz+5 more
wiley +1 more source
Dissecting Microscopic Colitis Immunopathophysiology: Insights From Basic Research
ABSTRACT Microscopic colitis is an inflammatory bowel disease (IBD) comprising two clinically undiscernible entities: collagenous colitis and lymphocytic colitis. Collagenous colitis associates with HLA genes and displays a Th1/Tc1–Th17/Tc17 profile with pericryptal myofibroblast activity, water malabsorption and secondary fluid loss due to altered ...
Andreas Münch+1 more
wiley +1 more source
Integrating critical view of safety and indocyanine green cholangiography to enhance safety in laparoscopic cholecystectomy: a retrospective cross-sectional study. [PDF]
Chartkitchareon A, Tullavardhana T.
europepmc +1 more source
Gut Microbiota as a Mediator Between Intestinal Fibrosis and Creeping Fat in Crohn's Disease
ABSTRACT Intestinal stricture remains one of the most challenging complications in Crohn's disease, and its underlying mechanisms are poorly understood. Accumulating evidence suggests that gut microbiota is significantly altered in stenotic intestines and may play a key role in the development of fibrogenesis in Crohn's disease.
Caiguang Liu+14 more
wiley +1 more source
Glucagon-Like Peptide-1 Receptor Agonists Lead to Gastrointestinal Benefits in Patients with Type 2 Diabetes: A Real-World Study. [PDF]
Hsu JH+6 more
europepmc +1 more source
ABSTRACT Objectives A novel partially self‐expandable metal stent (PCSEMS) with an anti‐migration system has recently become available during Endoscopic ultrasound‐guided hepaticogastrostomy (EUS‐HGS) but requires tract dilation. No previous study has compared the performance of dilation devices during EUS‐HGS.
Takeshi Ogura+15 more
wiley +1 more source
Abstract An 8‐year‐4‐month‐old, female, neutered labrador retriever with acute haemorrhagic diarrhoea was unresponsive to symptomatic and antibiotic treatment, and developed gastrointestinal protein loss leading to significant hypoalbuminaemia.
Luis Miguel Garcia Roldan+3 more
wiley +1 more source
Risk of Biliary Tract and Pancreatic Cancer Following Obstructive Sleep Apnea Diagnosis: Analysis of a National Health Insurance Database. [PDF]
Park MJ+5 more
europepmc +1 more source
Extrahepatic biliary obstruction secondary to a peritoneopericardial diaphragmatic hernia in a dog
Abstract A 16‐month‐old, entire, male dobermann presented for evaluation of emesis, anorexia and lethargy. Upon examination, the dog was found to be severely icteric. Serum biochemistry revealed an elevated total bilirubin and alkaline phosphatase, and computed tomographic imaging revealed a peritoneopericardial diaphragmatic hernia with abdominal ...
Emily Durocher+3 more
wiley +1 more source
Global burden of gallbladder and biliary diseases (1990-2021) with healthcare workforce analysis and projections to 2035. [PDF]
Dai F, Cai Y, Yang S, Zhang J, Dai Y.
europepmc +1 more source