Results 51 to 60 of about 595,039 (309)
Molecular and Cellular ProbesBiliary tract neoplasms, which originate from the intrahepatic or extrahepatic biliary epithelium, are relatively rare but diagnostically challenging types of tumours, and their morbidity and mortality have increased in recent years.
Tao Xu, Lingna Lyu, Junfu Zheng, Lei Li
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Cancer Medicine, 2021 This phase 1, multi‐center, nonrandomized, open‐label, dose‐escalation study consisted of Part A wherein merestinib 80 or 120 mg (40‐mg tablets) was administered orally QD during a 28‐day cycle to patients diagnosed with solid tumors and Part B wherein ...
Toshihiko Doi +9 more
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New advances in the management of biliary tract cancer [PDF]
, 2007 Biliary tract cancers are uncommon malignancies arising from biliary epithelium intrahepatically (peripheral cholangiocarcinoma), in the extrahepatic bile duct, the gall bladder and the ampulla of Vater.
Bridgewater, John, Imber, Charles
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INTRADUCTAL PAPILLARY MUCINOUS NEOPLASM: A NEW ENTITY AMONG BILIARY TRACT NEOPLASMS
Revista Española de Enfermedades Digestivas, 2020 Biliary tract intraductal papillary mucinous neoplasms (BT-IPMN) are a rare entity that develop within the bile duct lumen and are recognized as a precursor of invasive carcinoma in up to 40-80 % of cases.
Marta, Merayo-Álvarez +2 more
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An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
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Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
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Istoadenoma do ducto biliar comum
Revista do Colégio Brasileiro de CirurgiõesBiliary duct cystoadenomas are rare neoplasms, with about 120 cases described in the literature, including cystoadenomas and cystoadenocarcinomas. The authors report a case of cystoadenoma of the common bile duct in a 45-year-old woman with history of ...
José de Souza Andrade Filho +2 more
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Preoperative C-reactive protein as a prognostic factor for recurrence after surgical resection of biliary tract cancer [PDF]
Korean Journal of Clinical Oncology, 2015 Purpose: C-reactive protein (CRP) has been identified to be associated with cancer development and progression. However, the role of CRP in tumor recurrence is less well defined in biliary tract cancer.
Yoon-Hwan Nam, Min-Su Park, Sang-Mok Lee
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PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
MicroRNA 141 Expression Is a Potential Prognostic Marker of Biliary Tract Cancers
Gut and Liver, 2016 Background/AimsIn recent years, a large number of micro-ribonucleic acids (miRNAs) have been identified as putative prognostic biomarkers for solid cancers because of their role in controlling the expression of oncogenes and tumor suppressor genes.
Jaihwan Kim +3 more
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