Results 151 to 160 of about 46,698 (258)

Elevated COMMD1 Contributes to Cardiomyocyte Copper Efflux in Chronic Myocardial Ischemia: Insights From Rhesus Monkey

open access: yesCell Proliferation, EarlyView.
Elevated COMMD1 contributes to copper efflux in cardiomyocytes during chronic ischaemia in rhesus monkey hearts, regulated by XIAP through post‐translational modification. Our findings suggest a positive feedback loop among XIAP, COMMD1 and copper efflux, contributing to ischaemic cardiomyocyte loss.
Chen Li   +10 more
wiley   +1 more source

Endoscopic Management of Biliary Leakages. [PDF]

open access: yesVisc Med
Ellrichmann M   +3 more
europepmc   +1 more source

Foetal disruptive brain injuries: Diagnosing the underlying pathogenetic mechanisms with cranial ultrasonography

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
Abstract Antenatal destructive events affecting the central nervous system of the foetus lead to disruptive brain lesions that are often associated with impaired neurodevelopment. The pathogenesis of these lesions encompasses a range of causes, including haemorrhagic, embolic, or other vascular events; exposure to teratogens, such as drugs or substance
Ana Alarcón   +33 more
wiley   +1 more source

Gastric microbiota‐specific signatures in adults with obesity and Helicobacter pylori‐negative gastritis

open access: yesEuropean Journal of Clinical Investigation, EarlyView.
Abstract Background The role of the gastric microbiome in the pathophysiology of gastritis beyond Helicobacter pylori (HP) infection is poorly understood and has remained unexplored in patients with obesity. The aim of this study was to analyse gastric mucosa‐associated microbiota in patients with obesity and nonatrophic chronic gastritis in the ...
José Ignacio Martínez‐Montoro   +7 more
wiley   +1 more source

Autoimmunity in MASLD: Focus on autoantibodies, anti‐apolipoprotein A1 IgG and G protein‐coupled receptors

open access: yesEuropean Journal of Clinical Investigation, EarlyView.
This review outlines the potential role of anti‐GPCR autoantibodies in MASLD/MASH, given their involvement in a wide range of diseases and their possible contribution to MASLD/MASH pathophysiology. We also focused on anti‐ApoA1 autoantibodies, sharing functional features with anti‐GPCR autoantibodies and have been shown to promote liver steatosis in ...
Sabrina Pagano   +3 more
wiley   +1 more source

Incretin system and glucagon secretion in patients with chronic pancreatitis

open access: yesEuropean Journal of Clinical Investigation, EarlyView.
Diabetes of the exocrine pancreas (DEP) showed unclear incretin and glucagon dynamics. This cross‐sectional study compared 32 patients with chronic pancreatitis (wCP) and 60 without (w/oCP). Subjects wCP had worse beta‐cell function and lower incretin effect.
Gea Ciccarelli   +16 more
wiley   +1 more source

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