Elevated COMMD1 contributes to copper efflux in cardiomyocytes during chronic ischaemia in rhesus monkey hearts, regulated by XIAP through post‐translational modification. Our findings suggest a positive feedback loop among XIAP, COMMD1 and copper efflux, contributing to ischaemic cardiomyocyte loss.
Chen Li+10 more
wiley +1 more source
Endoscopic Management of Biliary Leakages. [PDF]
Ellrichmann M+3 more
europepmc +1 more source
Abstract Antenatal destructive events affecting the central nervous system of the foetus lead to disruptive brain lesions that are often associated with impaired neurodevelopment. The pathogenesis of these lesions encompasses a range of causes, including haemorrhagic, embolic, or other vascular events; exposure to teratogens, such as drugs or substance
Ana Alarcón+33 more
wiley +1 more source
Integrating critical view of safety and indocyanine green cholangiography to enhance safety in laparoscopic cholecystectomy: a retrospective cross-sectional study. [PDF]
Chartkitchareon A, Tullavardhana T.
europepmc +1 more source
Endoscopic retrograde cholangiopancreatography for the treatment of common bile duct dilatation with choledocholithiasis in children: a single-center retrospective cohort study of 58 cases. [PDF]
Wang X+7 more
europepmc +1 more source
Abstract Background The role of the gastric microbiome in the pathophysiology of gastritis beyond Helicobacter pylori (HP) infection is poorly understood and has remained unexplored in patients with obesity. The aim of this study was to analyse gastric mucosa‐associated microbiota in patients with obesity and nonatrophic chronic gastritis in the ...
José Ignacio Martínez‐Montoro+7 more
wiley +1 more source
Safety and effectiveness of modified laparoscopic transcystic biliary drainage in the treatment of choledocholithiasis: study protocol for a prospective single-arm clinical trial. [PDF]
Zhang YY+7 more
europepmc +1 more source
Advances in endoscopic management of biliary tract complications after liver transplantation
M. Arain, R. Attam, M. Freeman
semanticscholar +1 more source
This review outlines the potential role of anti‐GPCR autoantibodies in MASLD/MASH, given their involvement in a wide range of diseases and their possible contribution to MASLD/MASH pathophysiology. We also focused on anti‐ApoA1 autoantibodies, sharing functional features with anti‐GPCR autoantibodies and have been shown to promote liver steatosis in ...
Sabrina Pagano+3 more
wiley +1 more source
Incretin system and glucagon secretion in patients with chronic pancreatitis
Diabetes of the exocrine pancreas (DEP) showed unclear incretin and glucagon dynamics. This cross‐sectional study compared 32 patients with chronic pancreatitis (wCP) and 60 without (w/oCP). Subjects wCP had worse beta‐cell function and lower incretin effect.
Gea Ciccarelli+16 more
wiley +1 more source