Results 61 to 70 of about 997 (169)

Efficacy and Safety of Pharmacological, Endoscopic, and Surgical Treatments for Obesity: A GRADE‐Based Network Meta‐Analysis

Obesity, Volume 34, Issue 2, Page 279-293, February 2026.
ABSTRACT Objective This review compared antiobesity strategies—obesity management medications (OMM), endoscopic bariatric procedures (EBP), and metabolic bariatric surgery (MBS)—with lifestyle intervention, placebo, or no therapy (LSI/Pbo/NT). Methods This network meta‐analysis included randomized clinical trials comparing OMM, EBP, and MBS versus LSI ...
Maurizio De Luca, Ricardo V. Cohen, Amanda Belluzzi, Giuseppe Navarra, Nicola Di Lorenzo, Tarissa B. Z. Petry, Paolo Sbraccia, Luca Busetto, Silvio Buscemi, Rocco Barazzoni, Benedetta Ragghianti, Edoardo Mannucci, Matteo Monami   +12 more
wiley   +1 more source

A 19 year follow-up of a woman with lipoprotein lipase deficiency treated with biliopancreatic diversion

, 2015
We show the long-term efficacy and safety of modified biliopancreatic diversion for the treatment of LPL-deficiency. How this option compares with gene therapy is difficult to evaluate due to limited experience.
VACCARO, OLGA, COCOZZA, SARA, NOSSO, GABRIELLA, CAPALDO, BRUNELLA   +3 more
core   +1 more source

Human Skeletal Muscle Mitochondria Responses to Weight Loss Induced by Bariatric Surgery or Lifestyle Intervention

Acta Physiologica, Volume 242, Issue 2, February 2026.
ABSTRACT Aim We investigated how weight loss induced by bariatric surgery or lifestyle intervention affects skeletal muscle mitochondrial metabolism. Methods We studied two weight‐loss cohorts: RYSA (BMI ≥ 35 kg/m2; n = 39, including 18 with diabetes) undergoing bariatric surgery, and CRYO (BMI ≥ 30 kg/m2; n = 19) undergoing a lifestyle intervention ...
Birgitta W. van der Kolk, Sini Heinonen, James W. White, Anita Wagner, Jari E. Karppinen, Sina Saari, Maheswary Muniandy, Simo Metsikkö, Eugène T. Dillon, Per‐Henrik Groop, Tuure Saarinen, Carel W. Le Roux, Kirsi A. Virtanen, Neil G. Docherty, Eija Pirinen, Anne Juuti, Kirsi H. Pietiläinen   +16 more
wiley   +1 more source

Postabdominoplasty Wound Dehiscence in Bariatric Patients: Biliopancreatic Diversion Versus Gastric Bypass: A Preliminary Study

, 2014
Surgical procedures with an extended follow-up and therefore recognized as safe in literature are classified into 2 categories: procedures limiting the introduction of food mechanically (restrictive interventions such as adjustable gastric banding ...
Gentileschi, Stefano, Mingrone, Geltrude
core   +1 more source

The effect of bariatric surgeries on nonalcoholic fatty liver disease

The Saudi Journal of Gastroenterology, 2014
Objective: A review of published data addressing hepatic histopathological, metabolical, and functional changes following gastric banding, sleeve gastrectomy, gastric bypass surgery, and biliopancreatic with duodenal switch surgeries on nonalcoholic ...
Mazen Hassanian, Amnah Al-Mulhim, Atheer Al-Sabhan, Shaden Al-Amro, Fahad Bamehriz, Ayman Abdo, Hisham Al Khalidi   +6 more
doaj   +1 more source

Exploring the Relationship Between Obesity, Weight Loss and Health‐Related Quality of Life: An Updated Systematic Review of Reviews

Clinical Obesity, Volume 16, Issue 1, February 2026.
ABSTRACT The aim of this systematic literature review (SLR) of reviews was to update the evidence, established in a 2017 SLR, on the impact of obesity and weight loss by various interventions on health‐related quality of life (HRQoL). In total, eight SLRs and/or meta‐analyses published since 2017 were identified. The results consistently demonstrated a
Tone Nygaard Flølo, Hui‐Hsuan Liu, John Roger Andersen, Ronette L. Kolotkin   +3 more
wiley   +1 more source

A Rational Approach to Pharmacotherapy in Pregnancy

The Journal of Clinical Pharmacology, Volume 66, Issue 1, January 2026.
Abstract Most pregnant individuals are exposed to at least one medication, whether prescription or over the counter, during pregnancy. Despite the ubiquity of medication use in pregnancy, there remains no standardized framework to guide clinicians in selecting the most appropriate pharmacotherapy that balances maternal needs with fetal safety. This gap
Gregory W. Kirschen, Kevin Watt, Ahizechukwu C. Eke   +2 more
wiley   +1 more source

Outcomes of total hip arthroplasty in obese patients with and without preoperative weight loss: A systematic review and meta‐analysis

Journal of Experimental Orthopaedics, Volume 13, Issue 1, January 2026.
Abstract Purpose Obesity is often considered a relative contraindication to total hip arthroplasty (THA) due to presumed increased perioperative and postoperative risk. Consequently, obese patients are often advised to lose weight prior to THA. However, the effect of preoperative weight loss on THA outcomes remains uncertain.
Nils Meissner, Sonia Ramos‐Pascual, Katharina Ortwig, Floris van Rooij, Daniel Schrednitzki, Johannes Stoeve, Andreas M. Halder   +6 more
wiley   +1 more source

Efficacy and safety of European Medicines Agency (EMA)‐approved pharmacological, endoscopic, and surgical treatments in different classes of obesity: A network meta‐analysis of randomised controlled trials for the development of the SIO (Società Italiana Obesità) Italian guidelines for the diagnosis and treatment of overweight and obesity

Diabetes, Obesity and Metabolism, Volume 28, Issue 1, Page 358-378, January 2026.
Abstract Aims We aimed at comparing different approved strategies (obesity management medications—OMM, endoscopic bariatric procedures—EBP, and metabolic bariatric surgery—MBS) with lifestyle intervention/placebo/no therapy (LSI/Pbo/NT) for the treatment of different BMI‐based classes of obesity (i.e., overweight—BMI: 25–29.9 kg/m2; class I—BMI: 30–34 ...
Rocco Barazzoni, Matteo Monami, Silvio Buscemi, Luca Busetto, Maurizio De Luca, Giuseppe Navarra, Benedetta Ragghianti, Giovanni Antonio Silverii, Amanda Belluzzi, Edoardo Mannucci, Paolo Sbraccia   +10 more
wiley   +1 more source

Recent advances in metabolic and bariatric surgery [version 1; referees: 2 approved]

F1000Research, 2016
Obesity and its associated medical conditions continue to increase and add significant burden to patients, as well as health-care systems, worldwide.
Vance L. Albaugh, C. Robb Flynn, Robyn A. Tamboli, Naji N. Abumrad   +3 more
doaj   +1 more source