Results 311 to 320 of about 282,772 (364)

Severe Dietary Energy Restriction for Compensated Cirrhosis Due to Metabolic Dysfunction-Associated Steatotic Liver Disease: A Randomised Controlled Trial. [PDF]

J Cachexia Sarcopenia Muscle
Koutoukidis DA, Jebb SA, Tomlinson JW, Mozes FE, Pavlides M, Lacharie M, Saffioti F, Aveyard P, Cobbold JF.   +8 more
europepmc   +1 more source

A Novel Predictor Compared to the Model for End-Stage Liver Disease (MELD) and Child-Turcotte-Pugh (CTP) Scores for Predicting 30-Day Mortality in Patients With Liver Cirrhosis. [PDF]

Cureus
Dewi NNGK, Mariadi IK, Dewi NLPY, Pamungkas KMN, Dewi PISL, Sindhughosa DA.   +5 more
europepmc   +1 more source

New Function for Safety Signal Monitoring in MID-NET^®: The Case of an Anti-COVID-19 Drug. [PDF]

Clin Transl Sci
Okada Y, Ando T, Takahashi F, Watanabe K, Kajiyama K, Hasegawa T, Inomata S, Kinoshita Y, Watanabe S, Uyama Y.   +9 more
europepmc   +1 more source

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A simplified HPLC-based method for measuring unconjugated bilirubin, bilirubin-monoglucuronide, bilirubin-diglucuronide, and delta-bilirubin in plasma with increased conjugated bilirubin

Scandinavian Journal of Clinical and Laboratory Investigation, 2022
Prolonged icterus is an important and common problem in neonatology and accurate determination of the different bilirubin species, including differentiation between delta-bilirubin and mono- and di-conjugated bilirubin, is useful for diagnostic purposes. However, most bilirubin measurements routinely performed in the clinical laboratory are hampered by
Morten Hjuler Nielsen, Morten Mørk, Poul Madsen, Axel Brock   +3 more
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Goals of Treatment for Improved Survival in Primary Biliary Cholangitis: Treatment Target Should Be Bilirubin Within the Normal Range and Normalization of Alkaline Phosphatase.

American Journal of Gastroenterology, 2020
OBJECTIVES In primary biliary cholangitis (PBC), bilirubin and alkaline phosphatase (ALP) are widely established as independent predictors of prognosis.
C. F. Murillo Perez, M. Harms, K. Lindor, H. V. van Buuren, G. Hirschfield, C. Corpechot, A. J. van der Meer, J. Feld, A. Gulamhusein, W. Lammers, C. Ponsioen, M. Carbone, A. Mason, M. Mayo, P. Invernizzi, P. Battezzati, A. Floreani, A. Lleo, F. Nevens, K. Kowdley, Tony Bruns, G. Dalekos, N. Gatselis, D. Thorburn, P. Trivedi, X. Verhelst, A. Parés, H. Janssen, B. Hansen   +28 more
semanticscholar   +1 more source

Bilirubin is an antioxidant of possible physiological importance.

Science, 1987
Bilirubin, the end product of heme catabolism in mammals, is generally regarded as a potentially cytotoxic, lipid-soluble waste product that needs to be excreted.
R. Stocker, Y. Yamamoto, A. Mcdonagh, A. Glazer, B. Ames   +4 more
semanticscholar   +1 more source

Bilirubin as a signaling molecule

Medicinal research reviews (Print), 2020
For long time bilirubin was only considered as a potentially dangerous sign of liver diseases, but it now appears clear that it is also a powerful signaling molecule.
L. Vítek
semanticscholar   +1 more source

Structure of Bilirubin [PDF]

Nature, 1963
CONJUGATED bilirubins (esters) are formed within the liver cells from bilirubin and glucuronic or sulphuric acid. These compounds are very unstable because of the highly reactive central methylene bridge. They are oxidized rapidly by the air and react immediately with diazotized sulphanilic acid.
J. Fog, E. Jellum
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