Results 91 to 100 of about 37,436 (239)

Calculation Method for Tunnel Fire Smoke Exhaust Volume with Point Smoke Exhaust Mode

Chengshi guidao jiaotong yanjiu
Objective To address the lack of recognized numerical values and calculation methods for smoke exhaust volume of tunnel fire point smoke exhaust system specialized in GB 50016—2014 ′Code for fire protection design of buildings′, a definition of critical ...
WANG Rui
doaj   +1 more source

Flexural behavior of precast prestressed slabs with embedded building service systems

Structural Concrete, EarlyView.
Abstract Dry‐assembled precast concrete construction is rapidly spreading in many parts of the world due to the several advantages offered by industrialized construction. In order to speed up not only the assemblage of the structure, but also the full integrated building process, engineering systems (mechanical–electrical–plumbing) may be prefabricated
Bruno Dal Lago, Aleksei Abramov
wiley   +1 more source

Autosomal Dominant Hyper‐IgE Syndrome Patients Retain IL10‐Producing preTh17‐Cells That Are Activated by Opportunistic Pathogens and Support IgE Production

Allergy, EarlyView.
IL‐10 producing CCR6+Th‐cells are central memory T‐cells that express ROR‐γt and differentiate to Th17‐cells via an autocrine loop of STAT3‐activating cytokines (preTh17). STAT3‐deficient AD‐HIES patients lack Th17‐ and Tfh17‐cells but retain preTh17‐ and Th1/17‐cells.
Giorgia Moschetti, Chiara Vasco, Francesca Clemente, Paola Larghi, Sara Maioli, Edoardo Scarpa, Elena Carelli, Nadia Pulvirenti, Maria Lucia Sarnicola, Mariacristina Crosti, Manal Bel Imam, Willem van de Veen, Loris Rizzello, Sergio Abrignani, Lucia A. Baselli, Rosa Maria Dellepiane, Maria Carrabba, Giovanna Fabio, Jens Geginat   +18 more
wiley   +1 more source

Targeting protein–protein interactions with reversible covalent modalities: Non‐cysteine chemistries

British Journal of Pharmacology, EarlyView.
Abstract Protein–protein interactions (PPIs) are central to diverse cellular functions, and represent a rapidly expanding class of therapeutic targets. Advancements in covalent drug design have enabled small‐molecule drugs to overcome challenges associated with engaging these targets, such as limited durations of action and difficult‐to‐drug (expansive,
Ruchira Basu, Steven Fletcher
wiley   +1 more source

Circulating Musclin is associated with skeletal muscle function and subclinical cardiac dysfunction in patients with cancer

British Journal of Pharmacology, EarlyView.
Background and Purpose Musclin (osteocrin) is a skeletal muscle‐derived peptide that has been implicated in cardioprotective signalling pathways. Its relevance in cancer patients, who frequently experience muscle wasting and cardiotoxicity, remains unclear. This study aimed to determine whether circulating Musclin levels reflect functional capacity and
Jannek Brauer, Daniel Finke, Sebastian Romann, Norbert Frey, Joerg Heineke, Lorenz H. Lehmann   +5 more
wiley   +1 more source

Ezh2 Inhibits the Differentiation of Short‐Lived Effector CD8+ T Cells and Promotes T Cell‐Dependent Antitumor Immunity

Cancer Science, EarlyView.
The antitumor immune response is attenuated in T cell‐specific Ezh2 knockout mice. ABSTRACT Appropriate regulation of the differentiation balance between effector CD8+ T cells and memory CD8+ T cells is crucial for an appropriate immune response. We previously reported that the tumor suppressor menin suppresses the differentiation of CD8+ T cells into ...
Kenji Takagi, Junpei Suzuki, Yuko Matsuoka, Makoto Kuwahara, Taro Oshikiri, Masakatsu Yamashita   +5 more
wiley   +1 more source

A Survey of Methods for Constructing 3D Urban Models From Point Clouds

Computer Graphics Forum, EarlyView.
The survey outlines a general process for constructing 3D models from point clouds and categorizes the methods based on their use of templates, basic surface primitives, hybrid approaches, or linear primitives. Additionally, the survey reviews the datasets and benchmarks that are essential for testing and training the developed methods.
Chiara Romanengo, Silvia Biasotti, Bianca Falcidieno, Daniela Cabiddu, Elia Moscoso Thompson, Michela Spagnuolo   +5 more
wiley   +1 more source

SPINE: VAE‐driven Counterfactuals for Decision Boundary Maps

Computer Graphics Forum, EarlyView.
Abstract As Deep Learning models become increasingly complex, Explainable AI becomes essential for deploying machine learning classifiers. Decision Boundary Mapping (DBM) is a technique for visualizing a classifier's global decision boundary. Despite their relative success, current DBM methods rely on global inverse multidimensional projections that ...
I.M. Bloemen, V. Prasad, F. V. Paulovich
wiley   +1 more source

BIM to GIS and GIS to BIM

CAADence in Architecture, Back to command, 2016
Szabolcs Kari, László Lellei, Attila Gyulai, András Sik, Miklós Márton Riedel   +4 more
openaire   +1 more source

Review on Application of LiDAR Technology in Construction Life Cycle

Buildings
Light Detection and Ranging (LiDAR) technology has become a crucial tool in the construction industry, offering precise 3D data capture that addresses inaccuracies and provides accurate building information throughout various construction stages. Despite
Clyde Zhengdao Li, Zhe Chen, Tianliang Gao, Bing Xiao, Junlin Liu, Vivian W. Y. Tam, Khoa N. Le   +6 more
doaj   +1 more source