Results 131 to 140 of about 36,256 (219)

RNA Regulatory Networks: Key Hubs in the Panorama of Cancer and Emerging Therapeutic Targets

MedComm, Volume 7, Issue 3, March 2026.
RNA regulatory networks play a crucial role in the initiation and progression of cancer through various modes of RNA interactions. Notably, circulating RNAs have emerged as potential biomarkers, while targeted interventions in RNA regulatory networks facilitate precise therapeutic strategies. ABSTRACT Cancer is a global health challenge. The initiation
Xuan Yin, Zengkan Du, Shuya Jiang, Yan Liao, Changli Wang, Jiaqi Li, Haoling Zhang, Ting‐Ting Wei, Wangzheqi Zhang, Zui Zou   +9 more
wiley   +1 more source

Oncolytic virotherapy potentiates chemo-PD-1 immunotherapy by engaging chemo-resistant bystander CD8⁺ T cells. [PDF]

J Immunother Cancer
Yang Y, He J, Liang T, Li K, Lin Y, Wang H, Xi W, Ye S, Qiu D, Xie C, Hao Y, Li T, Yue S, Ye L, Chen X.   +14 more
europepmc   +1 more source

Navigating the cholesterol maze: Key insights on use of statins in neurodegenerative disorders

Neuroprotection, Volume 4, Issue 1, Page 30-47, March 2026.
The graphical abstract encapsulates the dual neuroprotective mechanisms of statins in neurodegenerative diseases, highlighting both cholesterol‐dependent and cholesterol‐independent pathways. By inhibiting 3‐hydroxy‐3‐methylglutaryl coenzyme A (HMG‐CoA) reductase, statins reduce cholesterol synthesis, leading to altered lipid raft structures that ...
Jun Han Kuan, Roshan S. Raghavan, Dawn Li Wei Koh, Wing Yeng Tan, Igor Iezhitsa, Renu Agarwal   +5 more
wiley   +1 more source

The ASFV CD2v protein inhibits apoptosis by inducing proteasomal degradation of Bim_EL via activation of the TPL2-MEK-ERK signaling pathway. [PDF]

J Virol
Zeng J, Zhang X, Zhao J, Li Q, Xiang Z, Shi F, Wang H, Weng W, Zhou Q, Gao P, Zhou L, Ge X, Han J, Guo X, Zhang Y, Yang H.   +15 more
europepmc   +1 more source

A Hybrid Nanosystem for Prostate Cancer Therapy: Codelivery of Enzalutamide and Curcumin via Selenium‐Embedded Mesoporous Silica and Chitosan Nanoparticles

ChemistryOpen, Volume 15, Issue 3, March 2026.
Herein, solvent extraction was selected for cetyltrimethylammonium bromide removal and the development of optimized Se‐embedded mesoporous silica nanoparticles, which were loaded with enzalutamide. Additionally, to improve the anticancer activity of Se@MSNPs‐Enz and curcumin bioavailability, curcumin‐loaded chitosan nanoparticles were prepared. This pH‐
Zahra Tavakoli, Khosro Khajeh, Bijan Ranjbar   +2 more
wiley   +1 more source

A BIM-Guided Virtual-to-Real Framework for Component-Level Semantic Segmentation of Construction Site Point Clouds. [PDF]

Sensors (Basel)
Zou Y, Liang T, Nabi JSRU, Xu Z, Zhou L, Xiong B.   +5 more
europepmc   +1 more source

Benchmarking Potential Construction Waste Streams and Their Climate Impact: Life Cycle Assessment‐Based Targets for Strategic Planning of Construction Processes

Sustainable Development, Volume 34, Issue S2, Page 280-295, March 2026.
ABSTRACT This study investigates how construction waste intensity affects greenhouse gas emissions (GHGe), analyzing data from 345 buildings constructed between 2007 and 2025. Using material waste rates (MWR) from previous cases, it predicts climate impacts based on typical material compositions.
Lea Hasselsteen, Aleksander P. Otovic, Harpa Birgisdóttir, Kai Kanafani   +3 more
wiley   +1 more source

Constructing an implementation plan for integrating green BIM into undergraduate architecture programs. [PDF]

Sci Rep
Ahmed N.
europepmc   +1 more source

Organic Linker Hybridization Induced Tunable and Intense Ultra Violet Emission From Zeolitic Imidazolate Framework‐8

ChemistrySelect, Volume 11, Issue 12, 26 March 2026.
Linker‐exchanged and solvated ZIF‐8 exhibit tunable, intense emission across the UVB‐UVC‐UVA range, a result of altered charge transfer dynamics due to the incorporation of benzimidazole as the new linker and the guest‐host interactions between the confined N,N‐dimethylformamide and the ZIF‐8 framework.
Jaideep Mor, Nimai Pathak, Mayanak Kumar Gupta, Ranjan Mittal, Sandeep Kumar Sharma   +4 more
wiley   +1 more source

Automated modeling to high level-of-detail composite object using spatial BIM objects and properties. [PDF]

Sci Rep
Lee JK, Cho D, Kim Y, Mo Y.
europepmc   +1 more source