Results 261 to 270 of about 294,501 (380)

IgD‐Expressing Mature B Cells Exhibit Enhanced Sensitivity to Glucocorticoid‐Induced Cell Death

European Journal of Immunology, Volume 56, Issue 1, January 2026.
Our study shows that mature B cells expressing IgD exhibit significantly higher sensitivity to glucocorticoid (GC)‐induced cell death. This elevated sensitivity is specifically dependent on GC receptor (GR) expression and is accompanied by enhanced activation as well as terminal differentiation of B cells.
Kais Almohammad, Marc Young, Sabine Vettorazzi, Franziska Greulich, Mahmoud Alkhatib, Jan Tuckermann, Hassan Jumaa, Corinna S. Setz   +7 more
wiley   +1 more source

Ivonescimab combined with chemotherapy shows promising efficacy in an ALK fusion-positive lung adenocarcinoma patient with ALK-TKI resistance: a case report. [PDF]

Front Oncol
Lin M, Gao Y, Deng J.
europepmc   +1 more source

Anti‐Neuroinflammation Activity of Essential Oils and Fatty Acids

Food Science &Nutrition, Volume 14, Issue 1, January 2026.
Neuroinflammation plays a pivotal role in the pathogenesis of neurodegenerative disorders, including Alzheimer's disease (AD) and Parkinson's disease (PD). Current pharmacological interventions, such as NSAIDs and corticosteroids, are limited by systemic toxicity and insufficient efficacy in targeting chronic neuroinflammatory processes.
Zelong Jin, Yige Song, Ahmed Attia Ahmed Abdelmoaty, Feng Lin, Jiujun Li, Xianyang Chen   +5 more
wiley   +1 more source

A hybrid extended Fermatean fuzzy WASPAS approach for optimal blockchain selection in building information modelling. [PDF]

Sci Rep
Fu P, Cao S, Xu D, Zhang X, Xie J.
europepmc   +1 more source

Logical Quality Check of Landscape BIM Models Using Visual Programming Languages† - Case Study on Calculating the Amount of Stormwater Management Facilities in Apartment Complexes -

Bok-Young Kim
openalex   +2 more sources

Highly effective combination of BRG1/BRM inhibitor with BET inhibitor or decitabine for high‐risk MECOM‐rearranged AML

HemaSphere, Volume 10, Issue 1, January 2026.
Abstract In AML with 3q26.2 rearrangements (r) the distal GATA2 hematopoietic enhancer becomes aberrantly relocated leading to activation of EVI1 expression. EVI1 is a transcriptional regulator that plays a role in proliferation and maintenance of a stem cell‐like phenotype in AML.
Warren Fiskus, Christopher P. Mill, Jessica Piel, Mike Collins, Murphy Hentemann, Branko Cuglievan, Christine E. Birdwell, Kaberi Das, John A. Davis, Hanxi Hou, Antrix Jain, Anna Malovannaya, Lauren B. Flores, Tapan M. Kadia, Naval Daver, Koji Sasaki, Koichi Takahashi, Danielle Hammond, Jian Wang, Sanam Loghavi, Xiaoping Su, Courtney D. DiNardo, Ruud Delwel, Kapil N. Bhalla   +23 more
wiley   +1 more source

Investigation of Aggregation-Induced Emission Mechanism of a Styrene Derivative: A Theoretical Unraveling of S₁/S₀‑Conical Intersection. [PDF]

ACS Omega
Aarzoo, Roy RK.
europepmc   +1 more source

Rps19R67∆ mutation creates a model of Diamond–Blackfan anemia and reveals downstream mediators of p53 pathway

HemaSphere, Volume 10, Issue 1, January 2026.
Abstract Diamond–Blackfan anemia (DBA) is a rare bone marrow failure syndrome accompanied by cardiovascular, skeletal, and urogenital abnormalities. Most of the affected individuals carry mutations in ribosomal proteins, including RPS19, a component of the 40S ribosomal subunit.
Juraj Kokavec, Tereza Turková, Björn Schuster, Jan Prochazka, František Spoutil, Kristína Jamrichová, Markéta Holečková, Karel Chalupský, Inken M. Beck, Jesús Ruberte, Matilde Vale, Lukáš Čermák, Tomáš Stopka, Radislav Sedlacek   +13 more
wiley   +1 more source

PLK1 inhibition enhances gemcitabine-induced apoptosis through PLK1-dependent ERK1/2-Bim and AKT1/Noxa signals in pancreatic cancer cells. [PDF]

Med Oncol
Lu B, Li H, Deng D, Wang Y.
europepmc   +1 more source

Assessment of the Effects of Cigarette Smoke on the Renal Morphology of WISTAR Rats

Journal of Applied Toxicology, Volume 46, Issue 1, Page 172-178, January 2026.
ABSTRACT Smoking is a major public health concern worldwide. The toxic components of cigarettes, such as nicotine, can cause abuse, dependence, and tissue damage. This study aimed to evaluate the effects of exposure to cigarette smoke on the renal morphology of Wistar rats.
Cristiane Gomes Fernandes Freire, Luana Aparecida Cunha, Mateus Andrade Stecca, Isabele Masson de Brito, Rafaella Riccio da Silva, Thiago Donizeth da Silva, Margarida Pereira Santos, Márcia Cristina Bizinotto de Assunção, Geraldo José Medeiros Fernandes, Evelise Aline Soares   +9 more
wiley   +1 more source