Results 181 to 190 of about 6,896 (262)

Progressive myoclonus epilepsy in Down syndrome with Alzheimer's disease: An 11‐year longitudinal study and proposed diagnostic red flags

Epilepsia Open, EarlyView.
Abstract Objective Individuals with Down syndrome (DS) face an ultra‐high risk of Alzheimer's disease (AD). Within this continuum, Progressive Myoclonus Epilepsy (PME) has emerged as a marker of advanced neurodegeneration. Building on our 2014 characterization of this syndrome, we aimed to define its long‐term natural history and pathological substrate.
Giuseppe d'Orsi, Ezio Calò, Maria Teresa Di Claudio, Carmela Pia Ferro, Umberto Costantino, Elio Perrone, Raffaela Rita Latino   +6 more
wiley   +1 more source

On‐site exposure to clinical epilepsy practice for experimental scientists engaged in epilepsy research: A pilot study by the ILAE commission on neurobiology

Epilepsia Open, EarlyView.
Abstract Educational initiatives that address the gap between basic/preclinical and clinical practices are important to effectively translate basic science discoveries to benefit patients. The ILAE Neurobiology Commission conducted a pilot project aimed at exposing basic and preclinical scientists engaged in epilepsy research to general clinical issues
Marco de Curtis, Giulia Battaglia, Gustavo Aguado‐Carrillo, Eleonora Aronica, Melody Asukile, Simona Balestrini, Carmen Barba, Tobias Baumgartner, Albert J. Becker, Francesca Bisulli, Patricia Braga, Nihan Carcak, Esper Cavalheiro, Norman Delanty, Lorenzo Ferri, Alon Friedman, Daniel Friedman, Marian Galovic, Jennifer N. Gelinas, Brenda Giagante, Rodrigo Henriquez‐Ch, Veena Kander, Silvia Kochen, David Krysl, Martin Kudr, Akio Ikeda, Mariana Legnani, Yicong Lin, Iris Martinez‐Juarez, Lorenzo Muccioli, Naluca Mwendaweli, Silvia Oddo, Çigdem Özkara, Jose Eduardo Peixoto‐Santos, Piero Perucca, Heidrun Potschka, Luisa Rocha, Helen Scharfman, Ingrid E. Scheffer, Rainer Surges, Chanez Charfi Triki, Reinaldo Uribe‐San‐Martin, Kette Valente, Erwin A. van Vliet, Yuping Wang, Benjamin Whatley, Jo M. Wilmshurst, Elza Marcia Yacubian, Alessandro De Rossi, Stefano de Curtis, Premysl Jiruska, David C. Henshall   +51 more
wiley   +1 more source

Bimodality in subaqueous dune height suggests flickering behavior at high flow. [PDF]

Nat Commun
de Lange SI, van de Vijsel RC, Torfs PJJF, Wallerstein NP, Hoitink AJF.   +4 more
europepmc   +1 more source

Cannabidiol reduces atypical absence seizures and epileptic spasms in a Gabrb3+/D120N mouse model of Lennox–Gastaut syndrome

Epilepsia Open, EarlyView.
Abstract Objective Lennox–Gastaut syndrome (LGS) is a drug‐resistant developmental and epileptic encephalopathy (DEE). Preclinical drug development for LGS is constrained by a lack of syndrome‐relevant animal models. We aimed to evaluate a Gabrb3+/D120N knock‐in (KI) mouse model of LGS by quantifying atypical absence seizures and epileptic spasms and ...
Thomas Harman, Laura A. Sharman, Ka Lai Yip, Miguel Bedoya‐Pérez, Vaishali Janve, Jonathon C. Arnold   +5 more
wiley   +1 more source

Predicting drainage capillary pressure curves in natural porous media by NMR-T₂ relaxometry: implications for CO₂ storage. [PDF]

Sci Rep
Markovic S, Kurochkin A, Efara M, Ahmed S, Al-Shalabi EW, AlAmeri W.   +5 more
europepmc   +1 more source

Spatial Variations in Methane Content and Their Main Controlling Factors of the Deep‐Buried Coalbed in the Nalinhe–Hengshan Area, Ordos Basin

Energy Science &Engineering, EarlyView.
Ash yield is the primary geological factor controlling the spatial variations in the total gas content of the deep‐buried coalbed methane in the Nalinhe‐Hengshan area, Ordos Basin. However, porosity dominates the differential enrichment of the free gas content of the deep‐buried coalbed methane in the Nalinhe‐Hengshan area, Ordos Basin.
Shi Yunhe, Wang Kangle, Wang Huaichang, Wang Yufei, Zhang Hui, Cao Jingjing, Yin Liangliang, Hu Xinyou, Liang Chao, Liu Mina   +9 more
wiley   +1 more source

Joint Inversion of Radionuclide Production Rate Data and Thermoremanent Magnetic Records over the Holocene. [PDF]

Sol Phys
Schanner MA, Nilsson A, Muscheler R.
europepmc   +1 more source

Iron Energy Carrier: Experimental Characterisation, Combustion Diagnostic and Benchmarking with Other Clean Metal Fuels

Energy Science &Engineering, EarlyView.
This study investigates how iron particles burn across a wide size range, revealing late‐stage nanoparticle release and a previously unrecognised shift in combustion behaviour near 118 µm. High‐speed imaging, PMT diagnostics and SEM analyses have been conducted.
Zakaria Mansouri
wiley   +1 more source

Introgression despite minimal hybridization: mating system modulates phenotypic associations with introgression in Clarkia. [PDF]

New Phytol
Sianta SA, Kern BR, Suri A, Brandvain Y, Moeller DA.   +4 more
europepmc   +1 more source

Revolutionizing Healthcare With Paper‐Based Nucleic Acid Testing

Exploration, EarlyView.
This work summarizes strategies to enhance paper‐based devices for nucleic acid testing. Key approaches include optimizing paper platforms, improving nucleic acid amplification, and refining labeling/signaling methods. These advancements aim to boost sensitivity, speed, and usability, making paper‐based diagnostics more effective for point‐of‐care ...
Hong Zhang, Yi Yang, Heng Li, Xiaolin Hu, Hui Xiao, Dou Wang, Sergio Benardini, Wei Gu, Yang Luo   +8 more
wiley   +1 more source