Results 51 to 60 of about 426,230 (326)

Dynamics of massive stellar black holes in young star clusters and the displacement of ultra-luminous X-ray sources

open access: yes, 2011
In low-metallicity environments, massive stars might avoid supernova explosion and directly collapse, forming massive (~25-80 solar masses) stellar black holes (MSBHs), at the end of their life.
Begelman   +73 more
core   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Binary clustering

open access: yesDiscrete Applied Mathematics, 2008
AbstractIn many clustering systems (hierarchies, pyramids and more generally weak hierarchies) clusters are generated by two elements only.This paper is devoted to such clustering systems (called binary clustering systems). It provides some basic properties, links with (closed) weak hierarchies and some qualitative versions of bijection theorems that ...
François Brucker   +1 more
openaire   +2 more sources

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

open access: yesMolecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh   +8 more
wiley   +1 more source

Binary Cumulants

open access: yesAdvances in Applied Mathematics, 2000
The author considers binary sequences (i.e. having letters from the set \(\{0,1\})\), and defines binary cumulants for joint probability distributions on binary sequences of finite length. Distributions on binary sequences of finite length are related to solve some fundamental mathematical problems (e.g. Hilbert's 17th problem).
openaire   +3 more sources

W 50 Morphology and the Dynamics of SS 433 Formation—The Origin of TeV Gammas from the Microquasar

open access: yesParticles
The precessing jets of microquasar SS 433 have punched through the supernova remnant W 50 from the explosion forming the compact object. The jets collimate before reaching beyond the shell, some 40 pc downstream, just the region of origin of TeV gamma ...
Michael Bowler
doaj   +1 more source

The frequency of planets in multiple systems

open access: yes, 2007
The frequency of planets in binaries is an important issue in the field of extrasolar planet studies, because of its relevance in estimating of the global planet population of our Galaxy and the clues it can give to our understanding of planet formation ...
Allen   +79 more
core   +2 more sources

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

open access: yesMolecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed   +8 more
wiley   +1 more source

On Binary Reducibility

open access: yesEuropean Journal of Combinatorics, 1988
Lovász and the reviewer proved that a connected graphic matroid M is the sum of two matroids of rank at least one if and only if M-e is disconnected for at least one element e. Cunningham generalized this for binary maroids. The present author gives a shorter proof for the general result, using geometric ideas of Mason and a theorem of Lucas on rank ...
openaire   +3 more sources

The Identity Politics of Qualitative Research. A Discourse Analytic Inter-text

open access: yesForum: Qualitative Social Research, 2006
We intend this paper to be read as an inter-text between selected FQS articles, which in one way or another engage in the identity politics of qualitative research, and the broader discussion of quality in the social sciences. Subjecting those texts to a
Pascal Dey, Julia C. Nentwich
doaj  

Home - About - Disclaimer - Privacy