Results 51 to 60 of about 431,891 (326)

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

Dynamics of black holes in de Sitter spacetimes [PDF]

open access: yes, 2012
Nonlinear dynamics in cosmological backgrounds has the potential to teach us immensely about our Universe, and also to serve as prototype for nonlinear processes in generic curved spacetimes.
Cardoso, Vitor   +5 more
core   +2 more sources

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Correction of UBV Photometry for Emission Lines

open access: yesOpen Astronomy, 2003
We investigate the effect on U,B,V magnitudes of the removal of emission lines from the spectra of some symbiotic stars and novae during their nebular phases.
Skopal A.
doaj   +1 more source

On Variation Mechanisms in Recurrent Nova IM Normae

open access: yesGalaxies, 2022
Light curves by Woudt and Warner (WW) of recurrent nova IM Nor show eclipse-like dips that they saw as too wide for eclipses alone, and interpreted as mainly a reflection effect due to irradiation of the companion (mass donor) star with some amplitude ...
R. E. Wilson
doaj   +1 more source

Identification of 13 DB + dM and 2 DC + dM binaries from the Sloan Digital Sky Survey

open access: yes, 2005
We present the identification of 13 DB + dM binaries and 2 DC + dM binaries from the Sloan Digital Sky Survey (SDSS). Before the SDSS only 2 DB + dM binaries and 1 DC + dM binary were known. At least three, possibly 8, of the new DB + dM binaries seem to
E. J. M. van den Besselaar   +18 more
core   +1 more source

Binary Cumulants

open access: yesAdvances in Applied Mathematics, 2000
The author considers binary sequences (i.e. having letters from the set \(\{0,1\})\), and defines binary cumulants for joint probability distributions on binary sequences of finite length. Distributions on binary sequences of finite length are related to solve some fundamental mathematical problems (e.g. Hilbert's 17th problem).
openaire   +2 more sources

Milli-arcsecond binaries [PDF]

open access: yesProceedings of the International Astronomical Union, 2007
AbstractAs part of an astrometric program (see Loinard et al. in this volume), we have obtained an unprecedented sample of high-resolution (~ 1 mas) VLBA images of several nearby young stellar systems. As was to be expected, these images revealed interesting new characteristics of these objects.
R. M. Torres   +3 more
openaire   +3 more sources

Identification of amino acids essential for angulin‐1/3 binding of the tricellular tight junction binder, angubindin‐1

open access: yesFEBS Open Bio, EarlyView.
Angubindin‐1 binds angulin‐1/‐3 at tricellular tight junctions, enhancing intestinal macromolecule permeation. Alanine scanning identified six essential residues (L562, L598, E638, V640, Y643, and K644) of angubindin‐1 critical for binding to angulin‐1/‐3 and permeation‐enhancing activity, providing insights for the development of targeted noninvasive ...
Taiki Kuzu   +8 more
wiley   +1 more source

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