Results 51 to 60 of about 8,111 (268)

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

The Search for Symbiotic Stars in the IPHAS Survey

open access: yesOpen Astronomy, 2012
We have started a project to search for symbiotic stars using the data from IPHAS, the Hα survey of the Northern Galactic plane. Candidates are selected from the IPHAS photometric catalogue based on their colors, combined with the information in the near-
Corradi R. L. M.
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

3D binary signatures [PDF]

open access: yesProceedings of the Tenth Indian Conference on Computer Vision, Graphics and Image Processing, 2016
Tenth Indian Conference on Computer Vision, Graphics and Image Processing ...
Siddharth Srivastava 0004, Brejesh Lall
openaire   +2 more sources

Symbiotic Stars: Observations Confront Theory

open access: yesOpen Astronomy, 2012
In this paper, I present and discuss some recent observational results which may have important implications for our understanding of late phases of binary evolution.
Mikołajewska J.
doaj   +1 more source

LONG-TERM ACTIVITY CHANGES OF UV PISOIUM

open access: yesOdessa Astronomical Publications, 2017
UV Psc has been observed since 1976 at the Ankara and Ege University Observatories. Mean light curves in B and V colours obtained using the maxima levels of observed light curves of the system.
V. Keskin   +5 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Jupiter Mass Binary Objects Show a Minimum Acceleration

open access: yesAstronomy
Forty-two Jupiter Mass Binary Objects (JuMBOs) have been discovered in the Trapezium Cluster: either brown dwarf stars or planets mutually orbiting in pairs.
Michael E. McCulloch
doaj   +1 more source

SBS 0802+529: A New Variable Star from the Second Byurakan Survey

open access: yesOpen Astronomy, 2012
A new emission line star was discovered on the plates of the Second Byurakan Survey (SBS). the follow up spectroscopy demonstrated that the object had a spectrum dominated by a late-type giant star with superposed hydrogen emission lines.
Chavushyan V.   +4 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

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