Results 81 to 90 of about 200,082 (276)

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Under-Developed and Under-Utilized Eclipsing Binary Model Capabilities [PDF]

open access: yesJournal of Astronomy and Space Sciences, 2012
Existing but largely unused binary star model capabilities are examined. An easily implemented scheme is parameterization of starspot growth and decay that can stimulate work on outer convection zones and their dynamos.
R. E. Wilson
doaj   +1 more source

Binary Cumulant Varieties [PDF]

open access: yesAnnals of Combinatorics, 2012
Minor revisions.
Sturmfels, Bernd, Zwiernik, Piotr
openaire   +2 more sources

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

The High Energy X-ray Probe (HEX-P): probing accretion onto stellar mass black holes

open access: yesFrontiers in Astronomy and Space Sciences
Accretion is a universal astrophysical process that plays a key role in cosmic history, from the epoch of reionization to galaxy and stellar formation and evolution. Accreting stellar-mass black holes in X-ray binaries are one of the best laboratories to
Riley M. T. Connors   +24 more
doaj   +1 more source

Constraining population synthesis models via the binary neutron star population

open access: yes, 2005
The observed sample of double neutron-star (NS-NS) binaries presents a challenge to population-synthesis models of compact object formation: the parameters entering into these models must be carefully chosen so as to match (i) the observed star formation
C. Kim   +5 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Astronomical Data Resources for Binary and Multiple Stars

open access: yesOpen Astronomy, 2015
Binary stars form a significant part of stellar population. They are registered and observed by a number of methods. This is the reason for variety of present-day resources of astronomical data dealing with binaries and multiples.
Kovaleva D.
doaj   +1 more source

THE DEPENDENCE OF ON- AND OFF-STATE GENERATIONS IN CLASSICAL MICROQUASARS FROM THE DISK DENSITY. 3-D NUMERICAL HYDRODYNAMICAL SIMULATIONS OF THE HIGH AND LOW MASS ACCRETION RATE IN ACCRETION DISK IN MICROQUASAR CYG X-1

open access: yesOdessa Astronomical Publications, 2018
In the present work we have computed and have compared the on- and off- generations in low and high mass accretion rate accretion disks. The comparison shows that in the case of low mass accretion rate in disk (10−10 solar mass per year) the ON-state time
V. Nazarenko
doaj   +1 more source

Binary Asteroid Encounters with Terrestrial Planets: Timescales and Effects

open access: yes, 2011
Many asteroids that make close encounters with terrestrial planets are in a binary configuration. Here we calculate the relevant encounter timescales and investigate the effects of encounters on a binary's mutual orbit. We use a combination of analytical
Benner   +13 more
core   +2 more sources

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