Results 61 to 70 of about 1,252,930 (316)

IMNM: integrated multi-network model for identifying pepper leaf diseases

Frontiers in Plant Science
As a vegetable crop with high economic value, the yield of pepper is often significantly restricted by leaf diseases, and the spots formed by these diseases on the surface of leaves are highly complex in color and texture characteristics. To overcome the
Zhaopeng Cai, Zhaopeng Cai, Nadia Farhana, Asif Mahbub Karim, Fengyan Zhai, Wenwen Huang, Meng Guo   +6 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

BinSlayer: Accurate Comparison of Binary Executables [PDF]

, 2013
As the volume of malware inexorably rises, comparison of binary code is of increasing importance to security analysts as a method of automatically classifying new malware samples; purportedly new examples of malware are frequently a simple evolution of ...
Martial Bourquin, Bourquin, Martial, Andy King, Robbins, Edward, King, Andy, Edward Robbins   +5 more
core   +1 more source

Slim binaries

Communications of the ACM, 1997
The traditional path to software portability among various hardware platforms has been the provision of "fat binaries", object files that contain multiple instruction sequences for different target architectures. This paper presents an alternative approach based on "slim binaries", files that contain a target-machine-independent program representation ...
Franz, Michael, Kistler, Thomas
openaire   +2 more sources

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Three-dimensional spatially localized binary-fluid convection in a porous medium [PDF]

, 2013
Three-dimensional convection in a binary mixture in a porous medium heated from below is studied. For negative separation ratios steady spatially localized convection patterns are expected.
Bergeon, Alain, Knobloch, Edgar, Lo Jacono, David   +2 more
core   +1 more source

Breakthrough in High-Efficiency Photocatalytic Degradation of Acebutolol by Advanced Binary CeO₂–MnO₂ Oxide System

Molecules
The sustainable catalytic efficacy of transition metal oxides (TMO) and rare earth element-based oxides positions them as pivotal materials for effectively treating contaminated wastewater.
Muthuraj Arunpandian, Tae Hwan Oh, Ganesan Sriram   +2 more
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Trial to increase the sensitivity of Brucella antigens treated with Binary ethylene imine as inactivated agent [PDF]

Journal of Veterinary Medical Research, 2007
kills Brucella cells by causing lysis of the membrane, so the phenol-heat killed brucella antigen may lake specificity as a result of destruction the majority of proteins in the cell wall.
Hussein K. Eldeen, Salwa S. Awad
doaj   +1 more source