Results 61 to 70 of about 4,365,484 (328)

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Research on Vulnerability Utilization Tool Development Framework [PDF]

Jisuanji gongcheng, 2018
At present,the number of binary vulnerabilities supported by existing vulnerability utilization platforms is not much,and the flexibility and development efficiency of these platforms is low.There are few utilization tool R & D and generation systems
WANG Yan,LIU Jiayong,LIU Liang,JIA Peng,LIU Luping
doaj   +1 more source

Retracted: Transient jet ejections associated with limit-cycle behaviors in the very high state of black hole binaries [PDF]

, 2023
Hajime Inoue
openalex   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

On the full automorphism group of a Hamiltonian cycle system of odd order

, 2015
It is shown that a necessary condition for an abstract group G to be the full automorphism group of a Hamiltonian cycle system is that G has odd order or it is either binary, or the affine linear group AGL(1; p) with p prime.
Buratti, Marco, Lovegrove, Graham J., Traetta, Tommaso   +2 more
core   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

The chromospherically active binary star EI Eridani II. Long-term Doppler imaging

, 2008
Data from 11 years of continuous spectroscopic observations of the active RS CVn-type binary star EI Eridani - gained at NSO/McMath-Pierce, KPNO/Coude Feed and during the MUSICOS 98 campaign - were used to obtain 34 Doppler maps in three spectroscopic ...
Baliunas, Barnes, Berdyugina, Berdyugina, Berdyugina, Berdyugina, Choi, Donati, Elstner, Fekel, Frasca, Granzer, Gray, Harvey, Hatzes, Hatzes, Hatzes, Holzwarth, Jeffers, Korhonen, Korhonen, Marsden, Moss, Nordström, O'Neal, O'Neal, Oláh, Oláh, Oláh, Oláh, Petit, Pietrinferni, Piskunov, Radick, Rice, Rice, Rice, Solanki, Solanki, Strassmeier, Strassmeier, Strassmeier, Strassmeier, Strassmeier, Strassmeier, Tuominen, Vogt, Washuettl, Willson, Çakırlı   +49 more
core   +1 more source

Impact of APOE ε4 Genotype Load on Cognitive Function and Lipid Metabolism in Patients With Cerebral Small Vessel Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Apolipoprotein ε4 (APOE ε4) is a potent genetic risk factor for Alzheimer's disease (AD). However, its role in cerebral small vessel disease (CSVD) remains unclear. Given the clinical and pathological similarities between CSVD and AD, this study aimed to investigate the associations of APOE ε4 gene dosage with cognitive function and
Tingru Jin, Haocheng Yang, Feng Liu, Sihao Lin, Junru Hu, Jian Wang, Yulan Gou   +6 more
wiley   +1 more source

Developmental, Neuroanatomical and Cellular Expression of Genes Causing Dystonia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Dystonia is one of the most common movement disorders, with variants in multiple genes identified as causative. However, an understanding of which developmental stages, brain regions, and cell types are most relevant is crucial for developing relevant disease models and therapeutics.
Darren Cameron, Nicholas E. Clifton, Daniel Cabezas de la Fuente, Peter Holmans, Nicholas J. Bray, Kathryn J. Peall   +5 more
wiley   +1 more source

Patterns of Postictal Abnormalities in Relation to Status Epilepticus in Adults

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Abnormalities on peri‐ictal diffusion‐weighted magnetic resonance imaging (DWI‐PMAs) are well‐established for patients with status epilepticus (SE), but knowledge on patterns of DWI‐PMAs and their prognostic impact is sparse. Methods This systematic review and individual participant data meta‐analysis included observational studies ...
Andrea Enerstad Bolle, Silvana Sarria‐Estrada, Thomas Bonduelle, Bertram Daniel Dynesen, Manuel Toledo, Zhu Chung Che, Kjell Heuser, Anastasios Chatzikonstantinou, Jérôme Aupy, Udaya Seneviratne, Estevo Santamarina Perez, Christoph Patrick Beier   +11 more
wiley   +1 more source