Results 111 to 120 of about 796,772 (273)

Separating the Role of Mixing‐Entropy on the Dynamics of Glass‐Forming Liquids

open access: yesAdvanced Science, EarlyView.
This research innovates by distinguishing entropy’s impact from enthalpy in materials through micro‐alloying. It finds liquid fragility decreases with minimal alloying content or increased element diversity. This clarifies entropy’s role and supports the entropy‐driven glass transition, guiding new material design.
Qing‐Zhou Bu   +7 more
wiley   +1 more source

Fast pH‐Driven Solubilization Method of Realgar (As4S4) to Reduce the Toxicity of Arsenic [As(III)] for Medicinal Purposes

open access: yesAdvanced Science, EarlyView.
Arsenic trioxide transformed acute promyelocytic leukemia therapy and shows promise against HIV. A new method to solubilize the mineral realgar produces different arsenic species depleting the main arsenic target, nuclear PML protein, and retaining effects on leukemic and HIV reservoir cells, while minimizing off‐target damage.
Bojana Lucic   +20 more
wiley   +1 more source

An Explainable Multimodal Artificial Intelligence Model Integrating Histopathological Microenvironment and EHR Phenotypes for Germline Genetic Testing in Breast Cancer

open access: yesAdvanced Science, EarlyView.
This study presents an explainable multimodal AI model, MAIGGT (Multimodal Artificial Intelligence Germline Genetic Testing), that combines whole‐slide histopathology with clinical data for accurate germline BRCA1/2 mutation prescreening. By integrating digital pathology and EHR phenotypes, MAIGCT enables cost‐effective, scalable hereditary breast ...
Zijian Yang   +23 more
wiley   +1 more source

A Soft‐Soft Contact Triboelectric Nanogenerator with a Ternary Four‐Phase Structure for Self‐Powered High‐Efficiency Dust Removal on Mars

open access: yesAdvanced Science, EarlyView.
The frequent dust storms and charged dust particles on Mars pose significant challenges to the power generation efficiency and service life of solar panels during exploration missions. This paper proposes a novel wind‐driven ternary four‐phase soft‐soft contact triboelectric nanogenerator (FPS‐TENG) for dust removal.
Fei Yang   +6 more
wiley   +1 more source

Deciphering Cell Type Abundance in Proteomics Data Through Graph Neural Networks

open access: yesAdvanced Science, EarlyView.
GraphDEC constructs pseudo bulk reference data using a mixup strategy, then learns low dimensional representations via autoencoders to model intra and inter dataset relationships. These are processed through a multi view adaptive neighborhood aware GNN, integrating reference, target, and joint graphs.
Zhiming Dai   +7 more
wiley   +1 more source

deepTFBS: Improving within‐ and Cross‐Species Prediction of Transcription Factor Binding Using Deep Multi‐Task and Transfer Learning

open access: yesAdvanced Science, EarlyView.
DeepTFBS leverages deep learning to predict transcription factor binding sites across species, integrating multi‐task and transfer learning approaches to improve performance in data‐scarce scenarios. This study demonstrates enhanced accuracy in intra‐ and cross‐species prediction, revealing conserved regulatory patterns and functional variants.
Jingjing Zhai   +8 more
wiley   +1 more source

Acoustic Wake in a Singular Isothermal Profile: Dynamical Friction and Gravitational-wave Emission

open access: yesThe Astrophysical Journal
We consider the motion of a circularly moving perturber in a self-gravitating, collisional system with a spherically symmetric density profile. We concentrate on the singular isothermal sphere, which, despite its pathological features, admits a simple ...
Gali Eytan   +2 more
doaj   +1 more source

AI‐Driven Defecation Analysis by Smart Healthcare Toilet: Exploring Biometric Patterns and Eu‐Tenesmus

open access: yesAdvanced Science, EarlyView.
A healthcare toilet system is introduced to passively measure defecation behavior. Real‐time data on stool dropping duration, thickness, and a newly defined “eu‐tenesmus” interval show correlations with stool form and gender differences. Results from 45 defecation events reveal a promising method for comprehensive defecation analysis.
Zhiquan Song   +16 more
wiley   +1 more source

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