Results 91 to 100 of about 1,311,479 (362)
We consider the two-variable fragment of first-order logic with one distinguished binary predicate constrained to be interpreted as a transitive relation.
Pratt-Hartmann, Ian
core +1 more source
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley +1 more source
Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?
Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley +1 more source
Partitioned binary relations [PDF]
We define the category of partitioned binary relations and show that it contains many classical diagram categories, including categories of binary relations, maps, injective maps, partitions, (oriented) Brauer diagrams and (oriented) Temperley-Lieb diagrams.
arxiv
On binary relations without non-identical endomorphisms
On every set A there is a rigid binary relation, i.e. such a relation R that there is no homomorphism (A,R)->(A,R) except the identity (Vopenka et al. [1965]). We state two conjectures which strengthen this theorem.
Tyszka, Apoloniusz
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Hyperstructures associated with binary relations
AbstractIn this paper, we deal with the partial hyperoperation introduced and studied by Corsini [1]. Various characterizations of the relations R, so that (H, ÕR) is a hypergroupoid, are given by means of the associated Boolean matrices. All hypergroupoids (H, ÕR) obtained from the set H, card H=2, 3, 4 are calculated.
Stefanos Spartalis, C. Mamaloukas
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Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova+18 more
wiley +1 more source
A theorem on the semigroup of binary relations [PDF]
PROOF. Necessity. Let p =p5p, where 5 ESx. Let o = 6p, then o2 = andp =po-. It is known in [1] that L(of) and L(p) are complete lattices in which joins are unions and, moreover, L(of) is completely distributive. If A CX, then it is easy to show that {t(A) =4t(4(A)) and +(A) =x(+1(A)) where c(A)EL(o-), ql(A)EL(p) and X(A)EL(a). Define the mapping 0 of L(
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This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu+12 more
wiley +1 more source
Kleene algebra axioms are complete with respect to both language models and binary relation models. In particular, two regular expressions recognise the same language if and only if they are universally equivalent in the model of binary relations.
Paul Brunet, Damien Pous
doaj +1 more source