Results 91 to 100 of about 1,311,479 (362)

The Finite Satisfiability Problem for Two-Variable, First-Order Logic with one Transitive Relation is Decidable

open access: yes, 2017
We consider the two-variable fragment of first-order logic with one distinguished binary predicate constrained to be interpreted as a transitive relation.
Pratt-Hartmann, Ian
core   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

open access: yesMolecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?

open access: yesMolecular Oncology, EarlyView.
Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley   +1 more source

Partitioned binary relations [PDF]

open access: yesMath. Scand. 113 (2013), no. 1, 30-52, 2011
We define the category of partitioned binary relations and show that it contains many classical diagram categories, including categories of binary relations, maps, injective maps, partitions, (oriented) Brauer diagrams and (oriented) Temperley-Lieb diagrams.
arxiv  

On binary relations without non-identical endomorphisms

open access: yes, 2000
On every set A there is a rigid binary relation, i.e. such a relation R that there is no homomorphism (A,R)->(A,R) except the identity (Vopenka et al. [1965]). We state two conjectures which strengthen this theorem.
Tyszka, Apoloniusz
core   +1 more source

Hyperstructures associated with binary relations

open access: yesComputers & Mathematics with Applications, 2006
AbstractIn this paper, we deal with the partial hyperoperation introduced and studied by Corsini [1]. Various characterizations of the relations R, so that (H, ÕR) is a hypergroupoid, are given by means of the associated Boolean matrices. All hypergroupoids (H, ÕR) obtained from the set H, card H=2, 3, 4 are calculated.
Stefanos Spartalis, C. Mamaloukas
openaire   +2 more sources

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

open access: yesMolecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova   +18 more
wiley   +1 more source

A theorem on the semigroup of binary relations [PDF]

open access: yesProceedings of the American Mathematical Society, 1969
PROOF. Necessity. Let p =p5p, where 5 ESx. Let o = 6p, then o2 = andp =po-. It is known in [1] that L(of) and L(p) are complete lattices in which joins are unions and, moreover, L(of) is completely distributive. If A CX, then it is easy to show that {t(A) =4t(4(A)) and +(A) =x(+1(A)) where c(A)EL(o-), ql(A)EL(p) and X(A)EL(a). Define the mapping 0 of L(
openaire   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Petri Automata [PDF]

open access: yesLogical Methods in Computer Science, 2017
Kleene algebra axioms are complete with respect to both language models and binary relation models. In particular, two regular expressions recognise the same language if and only if they are universally equivalent in the model of binary relations.
Paul Brunet, Damien Pous
doaj   +1 more source

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