Results 71 to 80 of about 891,196 (239)

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Ideals and Filters on Neutrosophic Topologies Generated by Neutrosophic Relations

Axioms
Recently, Milles and Hammami presented and studied the concept of a neutrosophic topology generated by a neutrosophic relation. As a continuation in the same direction, this paper studies the concepts of neutrosophic ideals and neutrosophic filters on ...
Ravi P. Agarwal, Soheyb Milles, Brahim Ziane, Abdelaziz Mennouni, Lemnaouar Zedam   +4 more
doaj   +1 more source

Binary Relational Data Model

PROBLEMS IN PROGRAMMING, 2017
The paper is related to the problem of data integration in the Semantic Web and  is a continuation of the previously published works, which was dedicated to the creation of mappings from the description logic (DL) into binary relational data model. In this paper, we define the binary relational data model, namely, its structure and algebra.
I.S. Chystiakova, V.A. Reznichenko
openaire   +2 more sources

The relation between degrees of belief and binary beliefs: A general impossibility theorem [PDF]

, 2019
Agents are often assumed to have degrees of belief (“credences”) and also binary beliefs (“beliefs simpliciter”). How are these related to each other? A much-discussed answer asserts that it is rational to believe a proposition if and only if one has a ...
Dietrich, Franz, List, Christian
core   +3 more sources

Probing the presence of a single or binary black hole in the globular cluster NGC 6752 with pulsar dynamics

, 2003
The five millisecond pulsars that inhabit NGC 6752 display locations or accelerations that are quite unusual compared to all other pulsars known in globular clusters. In particular PSR-A, a binary pulsar, lives in the cluster halo, while PSR-B and PSR-E,
Andrea Possenti, Bacon D., Dubath P., Fitchett M., Frank J., Michela Mapelli, Monica Colpi, Tauris T. M.   +7 more
core   +2 more sources

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Relational Contractions of Matkowski–Berinde–Pant Type and an Application to Certain Fractional Differential Equations

Fractal and Fractional
This paper concludes a few fixed-point outcomes involving almost Matkowski contraction-inequality of Pant type in a relational metric space. The findings established here enhance, expand, consolidate and develop several noted outcomes.
Doaa Filali, Faizan Ahmad Khan, Adel Alatawi, Esmail Alshaban, Montaser Saudi Ali, Fahad M. Alamrani   +5 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Solving Fractional Differential Equations via New Relation-Theoretic Fuzzy Fixed Point Theorems

Mathematics
In this paper, we present the notion of fuzzy R−F−contractive mappings and provide some fuzzy fixed point results in the setting of fuzzy metric spaces, which are endowed with binary relations.
Waleed M. Alfaqih, Salvatore Sessa, Hayel N. Saleh, Mohammad Imdad   +3 more
doaj   +1 more source