Results 81 to 90 of about 4,302,979 (374)

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

Molecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane, Jérôme Ambroise, Cédric van Marcke, Mieke Van Bockstal, Martine Berlière, Christine Galant, Hélène Dano, Médina Lougué, Elena Benidovskaya, Guy Jerusalem, Vincent Bours, Claire Josse, Jérôme Thiry, Aurélie Daumerie, Caroline Bouzin, Cyril Corbet, François P. Duhoux   +16 more
wiley   +1 more source

Relaxing the Φ-Family Auxiliary Functions and Related Results

Axioms
This article establishes the existence of fixed points and common fixed points for set-valued mappings satisfying an implicit-type contraction inequality involving a new auxiliary function in a complete metric space equipped with a binary relation ...
Salvatore Sessa, Yahya Almalki, Monairah Alansari, Muhammad Usman Ali, Essam Saleh Saad Said Al-Yari   +4 more
doaj   +1 more source

Common Fixed Point Theorems for Generalized Contractive Pair of Mappings in a Metric Space and Their Application to Fractional Calculus

Journal of Applied Mathematics, 2022
In this manuscript, we have established relation-theoretic version of some common fixed point results in metric space for generalized β−ϕ−Z-contractive pair of mappings furnished with an arbitrary binary relation R.
Priya Goel, Manoj Kumar, Dimple Singh, Kamal Kumar   +3 more
doaj   +1 more source

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

Molecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé, Lisa Hahnefeld, Katharina J. Wenger, Donat Kögel, Joachim Steinbach, Gerd Geisslinger, Michael W. Ronellenfitsch, Irmgard Tegeder   +7 more
wiley   +1 more source

The Finite Satisfiability Problem for Two-Variable, First-Order Logic with one Transitive Relation is Decidable

, 2017
We consider the two-variable fragment of first-order logic with one distinguished binary predicate constrained to be interpreted as a transitive relation.
Pratt-Hartmann, Ian
core   +1 more source

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

Molecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim, Myunghee Kang, Soyeon Jeong, Jisup Kim, Kyoung Oh Kim, Won‐Suk Lee, Jeong‐Heum Baek, Jung Ho Kim, Seungyoon Nam   +8 more
wiley   +1 more source

Suzuki-type fixed point theorems in relational metric spaces with applications [PDF]

Mathematica Moravica
In this paper, we establish a relation-theoretic version of the results presented by Kim et al. (Journal of Nonlinear and Convex Analysis, 16 (9) (2015), 1779-1786).
Khantwal Deepak, Pant Rajendra
doaj   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?

Molecular Oncology, EarlyView.
Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley   +1 more source

A theorem on the semigroup of binary relations [PDF]

Proceedings of the American Mathematical Society, 1969
PROOF. Necessity. Let p =p5p, where 5 ESx. Let o = 6p, then o2 = andp =po-. It is known in [1] that L(of) and L(p) are complete lattices in which joins are unions and, moreover, L(of) is completely distributive. If A CX, then it is easy to show that {t(A) =4t(4(A)) and +(A) =x(+1(A)) where c(A)EL(o-), ql(A)EL(p) and X(A)EL(a). Define the mapping 0 of L(
openaire   +1 more source