Results 81 to 90 of about 891,196 (239)
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Компютерні системи та інформаційні технологіїThe article is devoted to the research and implementation of methods and tools of finite predicate algebra for conducting a systematic analysis of the subject area, exemplified by the formalization of the task of finding a dance studio based on selected
Iryna VECHIRSKA, Anna VECHIRSKA
doaj +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
MathematicsNon-unique fixed-point theorems play a pivotal role in the mathematical modeling to solve certain typical equations, which admit more than one solution. In such situations, traditional outcomes fail due to uniqueness of fixed points.
Doaa Filali, Faizan Ahmad Khan
doaj +1 more source
Relation-based Galois connections: towards the residual of a relation [PDF]
, 2017 Inma P. Cabrera, Pablo Cordero, Manuel Ojeda-Aciego, Relation-based Galois connections: towards the residual of a relation, CMMSE 2017: Proceedings of the 17th International Conference on Mathematical Methods in Science and Engineering ( ISBN: 978-84-617-
Cabrera, Inma P. +2 more
core
On the generalization of Conway algebra
, 2018 In \cite{PrzytyskiTraczyk} J.H.Przytyski and P.Traczyk introduced an algebraic structure, called {\it a Conway algebra,} and constructed an invariant of oriented links, which is a generalization of the Homflypt polynomial invariant. On the other hand, in
Kim, Seongjeong
core +1 more source
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Aging and Cancer, EarlyView.Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Binary-Relational Storage Structures [PDF]
The Computer Journal, 1982 Any database, no matter how complex, can be represented as a set of binary-relationships. Consequently, a structure which can store such binary-relationships is logically sufficient as the storage mechanism for a general purpose database management system.
openaire +1 more source
On the existence of maximal elements: An impossibility theorem [PDF]
Most properties of binary relations considered in the decision literature can be expressed as the impossibility of certain ``configurations.'' There exists no condition of this form which would hold for a binary relation on a subset of a finite ...
Nikolai S Kukushkin
core