Results 181 to 190 of about 601,015 (329)

Matthiessen empirical relations in binary Al-Fe and Al-Si alloys.

open access: diamond, 1991
Shin-ya KOMATSU   +3 more
openalex   +2 more sources

Subuniformity of harmonic mean p$$ p $$‐values

open access: yesCanadian Journal of Statistics, EarlyView.
Abstract We obtain several inequalities on the generalized means of dependent p$$ p $$‐values. In particular, the weighted harmonic mean of p$$ p $$‐values is strictly subuniform under several dependence assumptions of p$$ p $$‐values, including independence, negative upper orthant dependence, the class of extremal mixture copulas, and some Clayton ...
Yuyu Chen   +3 more
wiley   +1 more source

Toward Anti‐Herpesviral PROTACs: Assessing the Challenges for Targeted Protein Degradation on the Example of Kaposi's Sarcoma‐Associated Herpesvirus Latency‐Associated Nuclear Antigen

open access: yesChemMedChem, EarlyView.
It is attempted to employ proteolysis‐targeting chimeras‐based targeted protein degradation to the viral protein “Latency‐associated Nuclear Antigen” from Kaposi's sarcoma‐associated herpesvirus. While ternary complex formation is detected via native mass spectrometry, protein degradation is not observed, presumably due to insufficient permeability ...
Aylin Berwanger   +10 more
wiley   +1 more source

Addressing Causality and Homogeneity Assumptions in Exposure‐Response Analyses

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Exposure‐response, or pharmacokinetic–pharmacodynamic (PKPD), analyses support many drug development decisions. It is typically applied without assessment of causality and homogeneity, where the latter refers to the assumption that the reason for variability in exposure is unimportant for the impact on response.
Mats O. Karlsson, Divya Brundavanam
wiley   +1 more source

The impact of dichotomization on network recovery. [PDF]

open access: yesBehav Res Methods
Sekulovski N   +3 more
europepmc   +1 more source

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