Results 61 to 70 of about 1,454,993 (340)

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

A New Binary Star System of EW Type in Draco: GSC 03905-01870

, 2018
Discovery of a new binary star system (GSC 03905-01870 = USNO-B1.0 1431-0327922 = UCAC4 716-059522) in the Draco constellation is presented. It was discovered during a search for previously unreported eclipsing binary stars through the ASAS-SN database ...
Barquin, Salvador
core   +3 more sources

The origin of very wide binary systems [PDF]

, 2009
The majority of stars in the Galactic field and halo are part of binary or multiple systems. A significant fraction of these systems have orbital separations in excess of thousands of astronomical units, and systems wider than a parsec have been ...
Bastian, D. Malmberg, de Grijs, Duquennoy, Goodwin, Kouwenhoven, Kouwenhoven, Kouwenhoven, M. B. Davies, M. B. N. Kouwenhoven, Mengel, P. Kroupa, Richard J. Parker, S. P. Goodwin   +13 more
core   +3 more sources

A wide star–black-hole binary system from radial-velocity measurements [PDF]

Nature, 2019
All stellar-mass black holes have hitherto been identified by X-rays emitted from gas that is accreting onto the black hole from a companion star. These systems are all binaries with a black-hole mass that is less than 30 times that of the Sun1–4. Theory
Jifeng Liu, Haotong Zhang, A. Howard, Zhongrui Bai, Youjun Lu, R. Soria, S. Justham, Xiang-dong Li, Zheng Zheng, Ting-gui Wang, K. Belczynski, J. Casares, Wei Zhang, Hailong Yuan, Yi-Ze Dong, Y. Lei, H. Isaacson, Song Wang, Y. Bai, Y. Shao, Qing Gao, Yilun Wang, Zexi Niu, Kaiming Cui, C. Zheng, Xiaoyong Mu, Lan Zhang, Wei Wang, A. Heger, Z. Qi, S. Liao, M. Lattanzi, Weimin Gu, Junfeng Wang, Jianfeng Wu, Lijing Shao, R. Shen, Xiaofeng Wang, J. Bregman, R. Di Stefano, Qing-zhong Liu, Zhanwen Han, Tianmeng Zhang, Huijuan Wang, Juanjuan Ren, Junbo Zhang, Jujia Zhang, Xiaoli Wang, A. Cabrera-Lavers, R. Corradi, R. Rebolo, Yongheng Zhao, Gang Zhao, Y. Chu, X. Cui   +54 more
semanticscholar   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

A Terrestrial Planet in a ~1 AU Orbit Around One Member of a ~15 AU Binary

, 2014
We detect a cold, terrestrial planet in a binary-star system using gravitational microlensing. The planet has low mass (2 Earth masses) and lies projected at $a_{\perp,ph}$ ~ 0.8 astronomical units (AU) from its host star, similar to the Earth-Sun ...
Abe, F., Albrow, M., Bennett, D. P., Bond, I. A., Botzler, C. S., Choi, J. -Y., Christie, G. W., DePoy, D. L., Drummond, J., Freeman, M., Friedmann, M., Fukui, A., Fukunaga, D., Gaudi, B. S., Gould, A., Han, C., Hwang, K. -H., Itow, Y., Jung, Y. K., Kaspi, S., Koshimoto, N., Kozłowski, S., Kubiak, M., Larsen, P., Lee, C. -U., Ling, C. H., Maoz, D., Masuda, K., Matsubara, Y., McCormick, J., Mróz, P., Muraki, Y., Namba, S., Natusch, T., Ngan, H., Ohnishi, K., Park, H., Philpott, L., Pietrukowicz, P., Pietrzyński, G., Pogge, R. W., Poleski, R., Porritt, I., Rattenbury, N. J., Saito, To., Shin, I. -G., Shvartzvald, Y., Skowron, J., Soszyński, I., Sullivan, D. J., Sumi, T., Suzuki, D., Szymański, M. K., Tan, T. -G., Tristram, P. J., Tsurumi, N., Udalski, A., Ulaczyk, K., Wada, K., Wyrzykowski, Ł., Yamai, N., Yee, J. C., Yock, P. C. M., Yonehara, A.   +63 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Microlensing Detections of Planets in Binary Stellar Systems

, 2007
We demonstrate that microlensing can be used for detecting planets in binary stellar systems. This is possible because in the geometry of planetary binary systems where the planet orbits one of the binary component and the other binary star is located at
Bozza V., Byeong‐Gon Park, Chang K., Cheongho Han, Chung‐Uk Lee, Dominik M., Dong‐Wook Lee, Duquennoy A., Eggenberger A., Ho‐Il Kim, Kayser R., Schneider P., Sun‐Ju Chung, Witt H. J., Young‐Soo Kim   +14 more
core   +1 more source

Impact flux of asteroids and water transport to the habitable zone in binary star systems [PDF]

, 2014
By now, observations of exoplanets have found more than 50 binary star systems hosting 71 planets. We expect these numbers to increase as more than 70% of the main sequence stars in the solar neighborhood are members of binary or multiple systems.
Bancelin, D., Dvorak, R., Eggl, S., Pilat-Lohinger, E.   +3 more
core   +2 more sources

Binary Neutron Star Mergers: Mass Ejection, Electromagnetic Counterparts, and Nucleosynthesis [PDF]

Astrophysical Journal, 2018
We present a systematic numerical relativity study of the mass ejection and the associated electromagnetic transients and nucleosynthesis from binary neutron star (NS) mergers.
D. Radice, A. Perego, K. Hotokezaka, S. Fromm, S. Bernuzzi, L. Roberts   +5 more
semanticscholar   +1 more source