LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Polar Circumtriple Planets and Disks around Misaligned Hierarchical Triple Stars
The Astrophysical JournalObservations of hierarchical triple-star systems show that misalignments are common both between the angular momentum vector of the inner binary and the outer companion orbit, and between the outer binary orbit and a circumtriple gas disk.
Stephen Lepp +2 more
doaj +1 more source
The Orbital Architecture of Qatar-6: A Fully Aligned Three-body System?
The Astronomical Journal, 2023 The evolutionary history of an extrasolar system is, in part, fossilized through its planets’ orbital orientations relative to the host star’s spin axis.
Malena Rice +7 more
doaj +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
, 2014 With our galactic evolutionary code that contains a detailed intermediate mass and massive binary population model, we study the temporal evolution of the galactic population of double neutron star binaries, mixed systems with a neutron star and black ...
Mennekens, N., Vanbeveren, D.
core +1 more source
Compact radio emission indicates a structured jet was produced by a binary neutron star merger [PDF]
Science, 2018 Merging produced a structured jet The binary neutron star merger event GW170817 was observed with gravitational waves and across the electromagnetic spectrum.
G. Ghirlanda +38 more
semanticscholar +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Using binary statistics in Taurus-Auriga to distinguish between brown dwarf formation processes
, 2017 Whether BDs form as stars through gravitational collapse ("star-like") or BDs and some very low-mass stars constitute a separate population which form alongside stars comparable to the population of planets, e.g. through circumstellar disk ("peripheral")
Béjar, V. J. S. +8 more
core +1 more source
GW170817: A Short Review of the First Multimessenger Event in Gravitational Astronomy
GalaxiesThe first detection of gravitational waves from the binary black merger GW150914 started the era of gravitational astronomy. The observation of the binary neutron star merger GW170817 and of its associated electromagnetic counterpart GRB 170817A started ...
Rosa Poggiani
doaj +1 more source
The Complete Evolution of a Neutron-star Binary through a Common Envelope Phase Using 1D Hydrodynamic Simulations [PDF]
Astrophysical Journal, 2019 Over 40 years of research suggests that the common envelope phase, in which an evolved star engulfs its companion upon expansion, is the critical evolutionary stage forming short-period, compact-object binary systems, such as coalescing double compact ...
T. Fragos +6 more
semanticscholar +1 more source