Results 71 to 80 of about 3,251 (296)

HNRNPU K181 Lactylation Drives Cervical Cancer Growth by Upregulating PHGDH and Reprogramming Serine Metabolism

open access: yesAdvanced Science, EarlyView.
Lactate in cervical cancer induces HNRNPU K181 lactylation, opposed by NAA50‐mediated acetylation and suppressed by Pazopanib. This lactylation enhances HNRNPU binding to PHGDH pre‐mRNA exon 1, maintaining exon 1‐containing transcripts and mRNA stability, thereby activating serine metabolism.
Chang Zhang   +6 more
wiley   +1 more source

Ultrasound‐Actuated Gene Editing in Human Kidney Organoids

open access: yesAdvanced Science, EarlyView.
Peptide‐stabilized nanoemulsions enable spatially controlled, ultrasound‐triggered delivery of gene‐editing proteins deep within human kidney organoid tissues. Focused acoustic pulses drive droplet vaporization, propelling cargo into target renal cells while preserving native tissue microarchitecture. This non‐viral platform improves both the depth and
Michael A. Miller   +6 more
wiley   +1 more source

SiC Powder Binder Jetting 3D Printing Technology: A Review of High-Performance SiC-Based Component Fabrication and Applications

open access: yesApplied Sciences
Silicon carbide (SiC) materials have demonstrated promising application prospects in modern manufacturing due to their outstanding physical and chemical properties.
Hong Liu, Feng Xiao, Yang Gao
doaj   +1 more source

Design guidelines for metal binder jetting

open access: yes
In addition to the general advantages of additive manufacturing technologies, such as the resource-efficient production of highly complex components, the metal binder jetting (MBJ) process enables a more cost-effective manufacturing of metal additive ...
Blunk, Heiko, Seibel, Arthur
core   +1 more source

Binder Jetting of Advanced Ceramics

open access: yes, 2022
The Binder Jetting BJ process is one of the most versatile additive manufacturing technologies in use. In this process a binder is locally jetted into a powder bed for the consolidation of a 3D structure, layer by layer.
Günster, Jens
core  

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

open access: yesAdvanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong   +24 more
wiley   +1 more source

Binder jetting process capability analysis on 17-4PH stainless steel

open access: yes, 2023
LAUREA MAGISTRALEMetal Binder Jetting (MBJ) ha il potenziale per essere una tecnologia innovativa nel campo della produzione additiva per produrre grandi quantità di componenti industriali con alta qualità.
Rua Neto, Pedro
core  

SERS Facemask for Rapid and Portable Sensing Mycobacterium Tuberculosis Antigens for TB Screening

open access: yesAdvanced Science, EarlyView.
Our study introduced an Au─Ag embedded covalent organic framework (U@COF) ‐mediated facemask for sensing TB antigen ESAT‐6/CFP‐10 complex in clinical droplet samples toward TB screening. Practical analysis of clinical samples demonstrated the availability of our facemask, which is capable of identifying the TB subjects (N = 17) from healthy candidates (
Lingzhi Chen   +20 more
wiley   +1 more source

Impacts of process-induced porosity on material properties of copper made by binder jetting additive manufacturing

open access: yesMaterials & Design, 2019
Binder Jetting (BJ) is an efficient, economical, and scalable Additive Manufacturing (AM) technology that can be used in fabricating parts made of reflective and conductive materials like copper, which have applications in advanced thermal and electrical
Ashwath Yegyan Kumar   +4 more
doaj   +1 more source

Harnessing Phase Separation for the Development of High‐Performance Hydrogels

open access: yesAdvanced Science, EarlyView.
ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao   +3 more
wiley   +1 more source

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