Results 31 to 40 of about 9,949 (243)

Binder jet 3D printing of 316L stainless steel: A Taguchi analysis of the dependence of density and mechanical properties on the printing parameters

open access: yesJournal of Materials Research and Technology
Most of the research on Binder Jetting 3D Printing of AISI316L stainless steel has focused on optimizing the sintering cycle, with less emphasis on the effect of printing parameters on the properties in the sintered state.
M. Zago   +3 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Powder-bed-based 3D printing with cement for sustainable casting

open access: yesJournal of Materials Research and Technology, 2023
3D printing allows for the cost-effective fabrication of moulds and can cast complex shapes. In this study, alumina cement and fine aggregates for refractories were used as the main raw materials, and saturation was adjusted to an appropriate level to ...
Seung-Yeop Chun   +8 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Experimental investigation into the thermal conductivity of gangue-cemented paste backfill in mine application

open access: yesJournal of Materials Research and Technology, 2022
Gangue-cemented paste backfill is one kind of paste backfill that is composed of cement, fly ash, and gangue, which is widely used in mining operation for controlling the strata movement and guaranteeing the safety of workplace.
Baiyi Li   +4 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Binder Saturation, Layer Thickness, Drying Time and Their Effects on Dimensional Tolerance and Density of Cobalt Chrome- Tricalcium Phosphate Biocomposite

open access: yes, 2021
Traditional metals such as stainless steel, titanium and cobalt chrome are used in biomedical applications (implants, scaffolds etc.) but suffer from issues such as osseointegration and compatibility with existing bone. One way to improve traditional biomaterials is to incorporate ceramics with these metals so that their mechanical properties can be ...
Ruprecht John   +2 more
openaire   +2 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Numerical Simulation and Experimental Study of the Thermal Wick-Debinding Used in Low-Pressure Powder Injection Molding

open access: yesPowders
Thermal wick-debinding, commonly used in low-pressure injection molding, remains challenging due to complex interactions between binder transport, capillary forces, and thermal effects.
Mohamed Amine Turki   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy