Results 221 to 230 of about 202,277 (297)

Multifaceted assessment of modifying and rejuvenating asphalt binders with recycled waste plastic and engine oil. [PDF]

Sci Rep
El-Sherbeni AA, Gabr AR, El-Badawy SM, Awed AM.   +3 more
europepmc   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

Protic ionic liquids as binders for carbon paste electrode fabrication. [PDF]

Commun Chem
Fotouhabadi Z, Bahrami M, Ghatee MH.
europepmc   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Improved protein binder design using β-pairing targeted RFdiffusion. [PDF]

Nat Commun
Sappington I, Toul M, Lee DS, Robinson SA, Goreshnik I, McCurdy C, Chan TC, Buchholz N, Huang B, Vafeados D, Garcia-Sanchez M, Roullier N, Glögl M, Kim CJ, Watson JL, Torres SV, Verschueren KHG, Verstraete K, Hinck CS, Benard-Valle M, Coventry B, Sims JN, Ahn G, Wang X, Hinck AP, Jenkins TP, Ruohola-Baker H, Banik SM, Savvides SN, Baker D.   +29 more
europepmc   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

Structure-activity relationships can be directly extracted from high-throughput crystallographic evaluation of fragment elaborations in crude reaction mixtures. [PDF]

Chem Sci
Grosjean H, Fieseler KK, Sanchez-Garcia R, Thompson W, Deane CM, von Delft F, Biggin PC.   +6 more
europepmc   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Engineering Single-Chain Antibody Fragment (scFv) Variants Targeting A Disintegrin and Metalloproteinase-17 (ADAM-17). [PDF]

Biomolecules
Kalantar M, Khorasani Buxton E, Reid KM, Bleyl D, Leitner DM, Raeeszadeh-Sarmazdeh M.   +5 more
europepmc   +1 more source