Results 71 to 80 of about 111,875 (254)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

USE OF LOCAL NATURAL SILICEOUS RAW MATERIAL AND WASTES FOR PRODUCTION OF HEAT-INSULATING FOAMCONCRETE

open access: yesВестник Дагестанского государственного технического университета: Технические науки, 2016
The article analyzes the resource base, reserves and the use of siliceous rocks, their economic feasibility of the use for production of building materials of new generation with low-energy and other costs.
V. U. Matsapulin   +4 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Assessment of some organic binders for the fabrication of uranium dioxide fuel pellets.

open access: yes, 1972
Uranium dioxide fuel pellets for water-cooled reactors are usually made by cold pressing and sintering UO2 powders with or without an organic binder.
Webb, CE, Ramm, EJ
core  

Preface to Atiyeh's Speeches As Delivered binders [PDF]

open access: yes, 2012
Atiyeh's preface to his self-selected collection of 'special speeches,' which he notes consists of 'as delivered' copies of the speeches. Atiyeh briefly describes the speech-writing process, what these speeches mean to him, and what he hopes for the ...
Atiyeh, Victor
core  

Development and design of binder systems for titanium metal injection molding: An overview [PDF]

open access: yes, 2013
Titanium metal injection molding (Ti-MIM) has been practiced since the late 1980s. Logically, the Ti-MIM practice follows the similar processes developed for the antecedent materials such as stainless steel and ceramics.
Neil Edmonds   +9 more
core   +1 more source

Evaluation of Polyvinyl Alcohol as Binder during Continuous Twin Screw Wet Granulation

open access: yesPharmaceutics
Binder selection is a crucial step in continuous twin-screw wet granulation (TSWG), as the material experiences a much shorter residence time (2–40 s) in the granulator barrel compared to batch-wise granulation processes. Polyvinyl alcohol (PVA) 4-88 was
Phaedra Denduyver   +4 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

On Nominal Regular Languages with Binders [PDF]

open access: yes, 2012
We investigate regular languages on infinite alphabets where words may contain binders on names. To this end, classical regular expressions and automata are extended with binders.
Kurz, Alexander   +5 more
core   +1 more source

Home - About - Disclaimer - Privacy