Results 251 to 260 of about 8,384,443 (422)

Interplay of integrins and selectins in metastasis

Molecular Oncology, EarlyView.
Here we review the role of integrins and their interplay with selectins in metastasis. The efficacy of integrin‐targeted therapies may be reduced in tumors where metastasis relies heavily on selectins. In certain tumors, integrins and selectins exhibit a synergistic interaction during intraperitoneal dissemination.
Diana Maltseva, Ashot Nersisyan, Alexander Tonevitsky   +2 more
wiley   +1 more source

Phosphorylation of ITIM motifs drives the structural transition of indoleamine 2,3-dioxygenase 1 between enzymatic and non-enzymatic states. [PDF]

Protein Sci
Hoffka G, Hornyák L, Székvölgyi L, Miskei M.   +3 more
europepmc   +1 more source

The Relation of Protein Binding to the Pharmacology and Antibacterial Activity of Penicillins X, G, Dihydro F, and K [PDF]

, 1947
Ralph Tompsett, SELMA M. SHULTZ, Walsh McDermott   +2 more
openalex   +1 more source

On ‘On binding’

Linguistics, 1981
George M. Horn, Robert D. Borsley
openaire   +2 more sources

Structural basis of STING binding with and phosphorylation by TBK1

Nature, 2019
Conggang Zhang, G. Shang, Xiang Gui, Xuewu Zhang, X. Bai, Zhijian J. Chen   +5 more
semanticscholar   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

Molecular characterization of a synthetic neutralizing antibody targeting p67 of Theileria parva. [PDF]

Protein Sci
Miersch S, Singer AU, Chen C, Fellouse F, Gopalsamy A, Costa LSE, Lacasta A, Chege H, Chege N, Nene V, Sidhu SS.   +10 more
europepmc   +1 more source

THE IODIDE TRAPPING AND BINDING FUNCTIONS OF THE THYROID [PDF]

, 1955
Solomon A. Berson, Rosalyn S. Yalow
openalex   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

The contribution of cyclic imide stereoisomers on cereblon-dependent activity. [PDF]

Chem Sci
Amako Y, Ichikawa S, Lloyd HC, Payne NC, Lin Z, Boghossian AS, Rees MG, Ronan MM, Roth JA, Zhu Q, Budnik B, Mazitschek R, Woo CM.   +12 more
europepmc   +1 more source