How Binding Affinity and Binding Specificity Map to Sequence Space. [PDF]
Liberles DA, Meyer MM.
europepmc +1 more source
A defect‐engineered Ag/Gd2O3:Nb2O5/Pt rare earth composite oxide memristor enables stable multilevel reservoir states through pulse driven conductance modulation. Experimentally measured device responses are incorporated into a device aware reservoir computing framework for CIFAR‐100 image classification, highlighting the potential of rare earth ...
Hammad Ghazanfar +9 more
wiley +1 more source
Directed evolution of a stem-helix-targeting antibody enables MERS-CoV cross-neutralization through enhanced binding affinity. [PDF]
Zhou P +19 more
europepmc +1 more source
Pressure‐Assisted Dimensional Transformation of 2D Hydrogenated Borophene into 0D Boron Quantum Dots
Hydrogenated borophene (HB) is transformed into distinct boron nanostructures through a solvent‐free thermal process. Under flowing nitrogen, hydrogen escape promotes reconstruction into B2O3 nanoplatelets, whereas hydrogen‐induced pressure under sealed conditions facilitates fragmentation into boron quantum dots.
Ozden Gunes Yildiz +11 more
wiley +1 more source
Enhancing Lithium Binding Affinity, Exchange Rate, and Hard-Soft Selectivity of Catenane Ligands by Post-Interlocking Modification. [PDF]
Yao Y +4 more
europepmc +1 more source
Preferential Interfacial Engineering of Hydrogels via Interdigitated Nanoparticle Assembly
Robust surface functionalization of hydrogel surfaces is performed via interdigitated metal nanoparticle assembly, inducing strong affinity with the hydrogel matrix. The partially exposed nanoparticle domains act as interfacial nanobridges that mediate both chemical and physical bonding with diverse materials, including small molecules, fluorous ...
Hyeonjin Kim +11 more
wiley +1 more source
Mutation-Aware Machine Learning Framework for Predicting Binding Affinity of Nirmatrelvir Analogs Targeting Coronavirus Main Proteases. [PDF]
Rahman MS, Hasan MM, M Islam S.
europepmc +1 more source
Lipoprotein‐mimicking nanoparticles (SL‐NPs), comprising Fe3O4@SiO2 cores coated with liposomal bilayers, selectively capture lipoproteins through protein corona formation. The resulting SL‐NP‐lipoprotein complexes can be removed by low‐speed centrifugation, thereby enhancing the purity of small extracellular vesicles (sEVs) isolated from human serum ...
Man‐Di Wang +7 more
wiley +1 more source
Cooperative molecular interaction networks govern PARP1 inhibitor selectivity and binding affinity. [PDF]
Feito A +7 more
europepmc +1 more source

