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The taxonomy of binding sites in proteins

Molecular and Cellular Biochemistry, 1978
Conservation of polypeptide fold and mode of ligand binding is frequently found within proteins of related function. Examples illustrating this phenomenon are taken from NAD linked enzymes, nucleotide binding proteins, polysaccharide binding proteins, heme binding proteins and enzymes with essential Fe--S complexes or zinc atoms.
Michael G. Rossmann, Patrick Argos
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Ethylene Binding Sites

1987
An account is given of the purification of the ethylene binding protein from developing cotyeldons of Phaseolus vulgaris. A correlation has been demonstrated between ethylene binding and sensitivity to the hormone in epicotyls of Pisum sativum. As this tissue also metabolises ethylene, this system could provide evidence for the hypothesis that ethylene
R. A. N. Williams   +4 more
openaire   +2 more sources

Localization of the Chaperone Binding-Site

Biochemical and Biophysical Research Communications, 1993
The hypothesis derived from models of the multi-oligomeric chaperone complex suggests that partially denatured proteins bind in a central cavity in the aggregate. To test this hypothesis, the molecular chaperone, alpha crystallin, was bound to partially denatured forms of gamma crystallin, and the binding site was visualized by immunogold localization.
Daniel L. Boyle   +2 more
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Melatonin Binding Sites

1993
Publisher Summary Melatonin is synthesized in vertebrate photoreceptors and constitutes the major known secretory product of the pineal gland. The synthesis and secretion of melatonin are photically regulated, restricted to the hours of darkness and inhibited by exposure to light during the night.
openaire   +2 more sources

MEASUREMENT OF TESTOSTERONE BINDING SITES

Acta Endocrinologica, 1970
ABSTRACT A Sephadex assay technique, in use in our laboratory for the study of steroid-protein interactions, allows expression of the molar concentration of a testosterone-binding component of human serum of high binding affinity in terms of the molar concentration of testosterone-binding sites: examples with model calculations are provided ...
openaire   +3 more sources

The Ribosome Binding Site Calculator

2011
The Ribosome Binding Site (RBS) Calculator is a design method for predicting and controlling translation initiation and protein expression in bacteria. The method can predict the rate of translation initiation for every start codon in an mRNA transcript.
openaire   +3 more sources

The Benzodiazepine Binding Sites of GABAA Receptors.

TIPS - Trends in Pharmacological Sciences, 2018
E. Sigel, M. Ernst
semanticscholar   +1 more source

TDP-43 condensation properties specify its RNA-binding and regulatory repertoire

Cell, 2021
Martina Hallegger   +2 more
exaly  

Nonspecific Binding—Fundamental Concepts and Consequences for Biosensing Applications

Chemical Reviews, 2021
Andreas Frutiger   +2 more
exaly  

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