Results 41 to 50 of about 259,971 (305)

VlPAG/DRN Microglia Drive Neuropathic Pain‐Induced Depression via a Defined Neuroimmune Axis

Advanced Science, EarlyView.
Peripheral nerve injury (SNI) induces neuropathic pain, activates midbrain microglia, and triggers an NLRP3–IL‐1β–dependent inflammatory cascade. IL‐1β signals through IL‐1R1 on vlPAG/DRN VGLUT2+ neurons (vlPAG/DRNGlu), inducing hyperexcitability and driving the vlPAG/DRNGlu→BNSTGABA circuit to produce the affective component of neuropathic pain ...
Jing Yang, Bing‐Jie Tang, Jia‐Yi Li, Shu‐Lan Xie, Shumin Duan, Junping Chen, Shengmei Zhu, Zhen‐Zhong Xu   +7 more
wiley   +1 more source

Marketing Search: An Interview with Pete Bell of Endeca and Gabriel Weinberg of DuckDuckGo

In the Library with the Lead Pipe, 2010
As it turns out, librarians aren’t the only ones competing with Google. In fact, we’re not even the only ones offering an alternative to Google when it comes to helping people find information. There’s Microsoft’s Bing, of course. And Yahoo!
Brett Bonfield
doaj  

WNK2 oncogenicity revealed by the discovery and functional characterization of novel gene isoforms in MYD88 mutated Waldenström’s Macroglobulinemia

Blood Cancer Journal
WNK2 is a known tumor suppressor in a set of solid tumors, including glioblastoma multiforme and pancreatic ductal adenocarcinoma. WNK2 functions are largely unknown beyond the kinase domain (KD)-dependent inhibition of ERK1/2 signaling.
Maria Luisa Guerrera, Xia Liu, Nickolas Tsakmaklis, Abigail L. Peachey, Amanda Kofides, John Hatcher, Andres Ramirez Gamero, Alberto Guijosa, Guang Yang, Hao Sun, Shirong Liu, Christopher J. Patterson, Kirsten Meid, Catherine Flynn, Ruben D. Carrasco, Andrew R. Branagan, Shayna R. Sarosiek, Jorge J. Castillo, Kenneth C. Anderson, Nikhil Munshi, Steven P. Treon, Zachary R. Hunter   +21 more
doaj   +1 more source

Triple‐Helix Biomolecules Construct Self‐Adaptive Multi‐Phase Interfaces for Dendrites Immunized Zinc Metal Anodes

Advanced Science, EarlyView.
A bio‐derived triple‐helix framework enables adaptive interphase engineering for aqueous Zn metal batteries. Directional Zn2+ migration channels and dynamic transformation into β‐sheet domains construct an optimized solid electrolyte interphase with flexible–rigid synergy, delivering dendrite‐free Zn deposition and exceptional long‐term battery cycling
Tianyi Wang, Jiahui Lu, Wei Gu, Jianfei Shi, Yuting Qin, Jian Yang, Di He, Zixia Lin, Jiabao Li, Bing Sun, Guoxiu Wang, Chengyin Wang   +11 more
wiley   +1 more source

EP300‐Mediated MTF1‐K218 Lactylation Buffers AR‐Driven Copper Overload to Suppress Cuproptosis in Castration‐Resistant Prostate Cancer

Advanced Science, EarlyView.
Androgen receptor (AR) drives copper accumulation in prostate cancer while inducing MTF1 to buffer copper toxicity. EP300‐mediated lactylation of MTF1 at K218 promotes its nuclear translocation and metallothionein expression, sequestering cytosolic copper and preventing mitochondrial cuproptosis.
Kai Li, Yong Wei, Yongshan Li, Yuxiang Dong, Jiancheng Lv, Mingzhi Yuan, Ao Shen, Fuyang Liu, Yetao Zhang, Youjian Li, Ruixi Yu, Yang Liu, Tong Zhao, Jun Wang, Kai Zhou, Zongyao Fan, Manning Wang, Jun Xu, Mulong Du, Min Gu, Bing Yao, Qingyi Zhu   +21 more
wiley   +1 more source

Perbandingan terjemahan bing translator dan google translate pada teks berita aljazeera.net

, 2023
Penelitian ini bertujuan untuk menganalisis dan membandingkan hasil terjemahan Bing Translator dan Google Translate kemudian menghadirkan terjemahan yang relevan dengan menggunakan metode penerjemahan bebas.
Muhamad iqbal jabal lutfi
core   +1 more source

Bing-Neel syndrome [PDF]

Arquivos de Neuro-Psiquiatria, 2017
A 75-year-old man with IgM-kappa restricted Waldenstrom macroglobulinemia (WM) was admitted due to paraparesis and sensory deficits of the lower extremities. Cerebrospinal fluid analysis revealed 140 cells/mm3, increased protein (295mg%), albumin quotient (16.57) and the presence of IgM-kappa chains in immunofixation electrophoresis.
Artemiadis K Artemios, Terentiou Aspasia, Kolokythopoulos Dimosthenis, Triantafyllou Nikos, Nikolaou George   +4 more
doaj   +3 more sources

A strategy to identify event specific hospitalizations in large health claims databases

BMC Health Services Research, 2022
Background Health insurance claims data offer a unique opportunity to study disease distribution on a large scale. Challenges arise in the process of accurately analyzing these raw data.
Joshua Lambert, Harpal Sandhu, Emily Kean, Teenu Xavier, Aviv Brokman, Zachary Steckler, Lee Park, Arnold Stromberg   +7 more
doaj   +1 more source

Interfacial Electric Field Engineering of High‐Entropy Heterostructures Triggering Self‐Limiting Reconstruction for Industrial‐Scale Electrocatalysis

Advanced Science, EarlyView.
An interfacial electric field engineering strategy is proposed to trigger the self‐limiting surface reconstruction of high‐entropy heterostructures. Driven by this built‐in field, the controlled sacrificial leaching of W evolves a robust active layer, enabling exceptional oxygen evolution performance and ultrastability at ampere‐level current densities
Liang Yan, Yueqi Zhang, Bing Zhang, Jingyi Ye, Hao Li   +4 more
wiley   +1 more source

Bayesian kinetic modeling for tracer-based metabolomic data

BMC Bioinformatics, 2023
Background Stable Isotope Resolved Metabolomics (SIRM) is a new biological approach that uses stable isotope tracers such as uniformly $$^{13}C$$ 13 C -enriched glucose ( $$^{13}C_6$$ 13 C 6 -Glc) to trace metabolic pathways or networks at the atomic ...
Xu Zhang, Ya Su, Andrew N. Lane, Arnold J. Stromberg, Teresa W. M. Fan, Chi Wang   +5 more
doaj   +1 more source