Results 251 to 260 of about 62,524 (313)

Pitolisant Inhibits Alcohol Drinking and Improves Withdrawal Negative Affect Through Lateral Habenula Histaminergic Signaling in Mice

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 1, January 2026.
Pitolisant, an FDA‐approved H3R antagonist, counteracts the rewarding and sedative effects of ethanol, reduces alcohol intake, and alleviates the negative affect during withdrawal. This might occur via the antagonism of presynaptic autoreceptors and heteroreceptors H3Rs in the lateral habenula, thereby activating the H2R/p‐CREB/BDNF signaling and ...
Yan Zhao   +13 more
wiley   +1 more source

General and Symptom‐Specific Illness Duration and Course as Predictors of Symptom Severity in Anorexia Nervosa

open access: yesInternational Journal of Eating Disorders, Volume 59, Issue 1, Page 99-110, January 2026.
ABSTRACT Objective Illness duration has been examined as a predictor of anorexia nervosa (AN) outcomes to mixed results, yet is frequently used to make treatment and prognosis decisions. More specific metrics, such as prior illness course (e.g., continuous vs.
Kira G. Venables   +5 more
wiley   +1 more source

Parallel Increase in Childhood Anorexia Nervosa and Early Puberty During the COVID‐19 Pandemic

open access: yesInternational Journal of Eating Disorders, Volume 59, Issue 1, Page 81-89, January 2026.
ABSTRACT Objective During the COVID‐19 pandemic, an increase in anorexia nervosa (AN), specifically childhood AN, as well as in central precocious puberty (CPP) and early‐onset puberty (EOP), was reported. The aim of this study was to explore whether there was a population‐level association between increases in both disorders and to discuss possible ...
Beate Herpertz‐Dahlmann   +4 more
wiley   +1 more source

The gut microbiota's role in bulimia nervosa and binge eating disorder: etiological insights and therapeutic implications from a scoping review. [PDF]

open access: yesNeurosci Appl
Tempia Valenta S   +6 more
europepmc   +1 more source

Adverse Childhood Experiences Predict Treatment Drop Out in Adolescents and Young Adults With Eating Disorders

open access: yesInternational Journal of Eating Disorders, Volume 59, Issue 1, Page 205-210, January 2026.
ABSTRACT Objective Childhood adversity is associated with elevated risk of developing an eating disorder. The objective of the current study was to examine whether different types of childhood adversity, such as parental separation or abuse exposure, predicted treatment completion in a sample of adolescents and young adults with eating disorders ...
David Lindenbach   +6 more
wiley   +1 more source

Greater Body Dissatisfaction at Admission Is Associated With Lower BMI at Discharge in Anorexia Nervosa: Predictive Validity of the Eating Pathology Symptoms Inventory

open access: yesInternational Journal of Eating Disorders, Volume 59, Issue 1, Page 90-98, January 2026.
ABSTRACT People with anorexia nervosa (AN) engage in dietary restriction and other weight loss behaviors that result in dangerously low body weight, leading to an increased risk for mortality and medical complications. Weight gain is one of the most important indicators of treatment progress and recovery for AN.
Danielle A. N. Chapa   +10 more
wiley   +1 more source

Mechanisms of Change in Cognitive-Behavioral Therapy for Adults With Binge-Eating Disorder: A Dynamic Structural Equation Modeling Approach. [PDF]

open access: yesInt J Eat Disord
Schmidt R   +8 more
europepmc   +1 more source

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