Results 181 to 190 of about 1,205,068 (305)

Short‐Term Outcomes of Two Interventions for Patients With Active Proliferative Diabetic Retinopathy in an Urban, Safety‐Net Hospital

open access: yesHealth Care Science, EarlyView.
An additional weekly resident‐run panretinal photocoagulation (PRP) clinic and implementation of a high‐risk registry and appointment system were associated with a decreased wait time from proliferative diabetic retinopathy (PDR) diagnosis to PRP, increased 3‐month PRP completion rates, decreased 3‐month loss to follow‐up, and increased ophthalmology ...
Paul S. Micevych   +3 more
wiley   +1 more source

Impact of Single‐Cell RNA Reference Selection for the Deconvolution of Breast Cancer Spatial Transcriptomics Datasets

open access: yesInternational Journal of Cancer, EarlyView.
ABSTRACT Spot‐based spatial transcriptomics (ST) allows for unbiased gene expression analysis within tissue architecture, overcoming the limitations of single‐cell RNA sequencing (scRNA‐seq) by preserving spatial context. However, the high spatial resolution in ST leads to cellular heterogeneity within spots, requiring computational deconvolution to ...
Stefan Altendorfer   +2 more
wiley   +1 more source

A cross‐sectional study of intimate partner violence and associated factors in women with high‐risk pregnancies: Implications for perinatal care in a tertiary obstetrics hospital

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective This study estimates the prevalence of intimate partner violence during pregnancy (IPVP) and identifies associated psychosocial and mental health factors among women with high‐risk pregnancies. Materials and Methods A cross‐sectional study was conducted among 199 women with high‐risk pregnancies attending a tertiary obstetrics and ...
Diana Pimentel‐Nieto   +3 more
wiley   +1 more source

Conserved SERPINE2 function maintains ovarian estrogen production to support fertility in goats and mice

open access: yesiMetaOmics, EarlyView.
Single‐nucleus RNA sequencing and functional profiling of goat ovaries with divergent litter sizes revealed prolificacy‐associated granulosa cell (GC) states characterized by enhanced proliferation‐ and steroidogenesis‐related features, together with altered predicted cell–cell communication.
Sanbao Zhang   +6 more
wiley   +1 more source

Benchmarking gut microbiome indices within and across populations

open access: yesiMetaOmics, EarlyView.
We compared 10 widely used gut microbiome indices in 12,561 American Gut Project participants and 10 external cohorts, testing how well each distinguished people with healthy lifestyles, responded to 79 environmental factors, and associated with 14 chronic conditions. No single index performed best on all three tasks.
Yu Sun   +6 more
wiley   +1 more source

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