Results 61 to 70 of about 1,205,068 (305)

Lipidomic Profile Reconstruction of Therapeutic Membrane Targets Using Physics‐Based Optimization with Limited Activity Data

open access: yesAdvanced Science, EarlyView.
Using a minimal set of experimentally labeled antimicrobial and non‐antimicrobial peptides, we reconstruct the effective lipid composition of a pathogenic membrane ‐demonstrated at the example of bacterial membranes‐ through a physics‐based evolutionary molecular dynamics (Evo‐MD) approach. Optimization based on peptide insertion reveals broad‐spectrum
Maximilian Krebs, Herre Jelger Risselada
wiley   +1 more source

Comparison of hydrological model ensemble forecasting based on multiple members and ensemble methods

open access: yesOpen Geosciences, 2021
Ensemble hydrologic forecasting which takes advantages of multiple hydrologic models has made much contribution to water resource management. In this study, four hydrological models (the Xin’anjiang model (XAJ), Simhyd, GR4J, and artificial neural ...
Wang Jie   +6 more
doaj   +1 more source

Quasi-binomial series-fed array for performance improvement of millimeter-wave antenna for 5G MIMO applications

open access: yesEngineering Science and Technology, an International Journal, 2023
A quad-port MIMO antenna based on a quasi-binomial series-fed array is presented in this paper for n257 and n258 millimeter-wave applications with an investigation of additional loaded patches on performance enhancement of the conventional binomial ...
Md. Abu Sufian, Niamat Hussain, Nam Kim
doaj   +1 more source

Some functional equations related to binomial coefficient summation [PDF]

open access: yes, 1967
The general solution has been obtained of two functional equations suggested by a binomial coefficient identity proved by Gould and Kaucký[J. Combinatorial Theory. 1 (1966), 233–247]
Carlitz, L.
core   +1 more source

Artificial Intelligence‐Guided Phenotypic Drug Repurposing Against Streptococcus pneumoniae

open access: yesAdvanced Science, EarlyView.
Integrated artificial intelligence (AI) ensembles identify highly potent repurposed drugs against Streptococcus pneumoniae. Prospective virtual screening of 6747 drugs uncovers nine active candidates, including thiostrepton. This drug exhibits low picomolar potency and bypasses established resistance in multidrug‐resistant strains, demonstrating an ...
Joshua S. Fitch   +6 more
wiley   +1 more source

A Note on the Difference of Powers and Falling Powers

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 2021
Combinatorial sums and binomial identities have appeared in many branches of mathematics, physics, and engineering. They can be established by many techniques, from generating functions to special series.
Taoufik Sabar
doaj   +1 more source

On the errors and comparison of Vega estimation methods [PDF]

open access: yes, 2003
This article discusses convergence problems when calculating Vega (option sensitivity to volatility) that arise from discretization errors embedded in the lattice approach.
Shackleton, M B, Chung, S L
core   +4 more sources

TSTScope Unifies Single‐Cell Multi‐Omics to Identify Functional T Cell States Predictive of Immunotherapy Response

open access: yesAdvanced Science, EarlyView.
TSTScope is an interpretable AI framework that integrates single‐cell transcriptomes with TCR information through curated gene‐program constraints. By linking receptor context to functional T cell states, it reveals response‐associated tumor‐specific T cell programs in lung cancer immunotherapy cohorts and defines an MPR score associated with ...
Shiwei Cao   +8 more
wiley   +1 more source

The Janjić–Petković Inset Counting Function: Riordan Array Properties and a Thermodynamic Application

open access: yesMathematics
Let q1+⋯+qn+m objects be arranged in n rows with q1,…,qn objects and one last row with m objects. The Janjić–Petković counting function denotes the number of (n+k)-insets, defined as subsets containing n+k objects such that at least one object is chosen ...
Marcus Kollar
doaj   +1 more source

Dual‐line Genome‐scale CRISPR Screening Enables Robust Target Gene Discovery

open access: yesAdvanced Science, EarlyView.
A species‐optimized CRISPR platform integrates efficient piggyBac delivery, genome‐scale sgRNA libraries, and parallel screening in two independently engineered Bactrocera dorsalis Cas9 cell lines. Cross‐line consensus analysis filters line‐specific effects, enriches candidates with reproducible in vivo phenotypes, and reveals conserved, species ...
Ziniu Li   +9 more
wiley   +1 more source

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