Results 121 to 130 of about 44,005 (262)

Development and Analytical Validation of a Laboratory‐Customized TaqMan‐MGB Probe Method for CYP2C19 Genotyping

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
A laboratory‐customized, open‐sequence TaqMan‐MGB probe assay was developed for detecting CYP2C19*2 and CYP2C19*17 polymorphisms using dried blood spot‐derived DNA. The assay demonstrated allele‐specific discrimination, candidate LODs of 1.17 × 102 copies/μL for CYP2C19*2 and 0.94 × 103 copies/μL for CYP2C19*17, and repeatability with CVs below 10%. In
Yaqun Liu   +7 more
wiley   +1 more source

Molecular dynamics simulations of oleuropein diffusion in chitosan‐based nanoparticles

open access: yesJournal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND This study explores the diffusion mechanisms of oleuropein (OLE), a promising polyphenolic compound, within chitosan‐based nanoparticles using molecular dynamics simulations. Chitosan nanoparticles serve as drug delivery carriers, leveraging biocompatibility and tunable release properties influenced by environmental factors such as ...
Bernardino Tirri   +3 more
wiley   +1 more source

Perceived Suitability for Being a Dental Hygienist and Self‐Compassion: A 6‐Month Longitudinal Cohort Study

open access: yesJournal of Dental Education, EarlyView.
ABSTRACT Objectives Perceived professional suitability—students' judgment of whether they are well‐suited to their profession—may shift within a semester, yet longitudinal evidence in dental hygiene education is limited. We examined 6‐month changes in perceived suitability and their psychological associations.
Maya Izumi   +2 more
wiley   +1 more source

An Exploratory Comparative Analysis of Mixed Reality Simulation Versus 3D‐Printed Models for Undergraduate Training in Third Molar Removal

open access: yesJournal of Dental Education, EarlyView.
ABSTRACT Purpose/Objectives To compare the effectiveness of MR simulation and 3D‐printed models in training undergraduate students in wisdom tooth removal, and to assess students’ perceptions of the MR simulator. Methods Students trained first on either the MR simulator or 3D‐printed plastic models and then repeated the training using the other method ...
Ruza Bjelovucic   +5 more
wiley   +1 more source

Total Immunoglobulin G Variation Through the Phenological Cycle of Migrant and Resident Lesser Long‐Nosed Bats (Leptonycteris yerbabuenae) in the Drylands of Mexico and Its Relationship With Bacterial Killing‐Ability of Plasma

open access: yesJournal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
ABSTRACT Bats have unique immunological characteristics among vertebrates. Understanding how the immune system responds during the life cycle of bat populations is crucial for grasping how their defenses against infection vary during critical life events.
David Alfonso Rivera‐Ruiz   +6 more
wiley   +1 more source

Stable Cuts, NAC‐Colourings and Flexible Realisations of Graphs

open access: yesJournal of Graph Theory, EarlyView.
ABSTRACT A (2‐dimensional) realisation of a graph G $G$ is a pair ( G , p ) $(G,p)$, where p $p$ maps the vertices of G $G$ to R 2 ${{\mathbb{R}}}^{2}$. A realisation is flexible if it can be continuously deformed while keeping the edge lengths fixed, and rigid otherwise.
Katie Clinch   +5 more
wiley   +1 more source

A two‐stage model for precise identification and Gleason grading of clinically significant prostate cancer: a hybrid approach

open access: yesJournal of Medical Radiation Sciences, Volume 72, Issue 1, Page 93-105, March 2025.
This study developed a two‐stage model using radiomics‐based multiparametric MRI and clinical indicators to help identify and grade clinically significant prostate cancer. The model showed promising levels of diagnostic accuracy and predictive performance.
Yuyan Zou   +10 more
wiley   +1 more source

Statistical Downscaling of Daily Temperature and Precipitation From Regional Climate Models in Complex Mountain Terrain

open access: yesInternational Journal of Climatology, EarlyView.
The study provides insights for post‐processing climate model output in complex terrain, useful for climate change impact models. We compared different bias adjustment and downscaling techniques from quantile delta mapping to simple lapse rates. We developed a new spatial downscaling method based on principal components analysis, which showed superior ...
Michael Matiu   +4 more
wiley   +1 more source

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