Results 141 to 150 of about 389,511 (337)

Gut microbiota–derived short‐chain fatty acids regulate group 3 innate lymphoid cells in HCC

open access: yesHepatology, EarlyView., 2022
Abstract Background and Aims Type 3 innate lymphoid cells (ILC3s) are essential for host defense against infection and tissue homeostasis. However, their role in the development of HCC has not been adequately confirmed. In this study, we investigated the immunomodulatory role of short‐chain fatty acids (SCFAs) derived from intestinal microbiota in ILC3
Chupeng Hu   +11 more
wiley   +1 more source

PITTING THE BINOMIAL DISTRIBUTION TO THE SEX DISTRIBUTION OF FAMILY CHILDREN

open access: yesIranian Journal of Public Health, 1975
در اين مطالعه 2833 خانوار (1402 خانوار مسلمان و 1431 خانوار ارامنه) را که مجموعاً 11324 فرزند (بطور متوسط 4 فرزند براي هر خانوار) داشته اند از طرح مجيديه " طرح بررسي بعد خانوار" استخراج مورد استفاده قرار گرفته است. خانوارهاي مورد مطالعه کليه خانواده هايي
Firooz Azordcgan
doaj  

Real Options using Markov Chains: an application to Production Capacity Decisions [PDF]

open access: yes
In this work we address investment decisions using real options. A standard numerical approach for valuing real options is dynamic programming. The basic idea is to establish a discrete-valued lattice of possible future values of the underlying ...
Dalila B. M. M. Fontes   +2 more
core  

Depression Polygenicity and Disease Activity and Disability Worsening in Multiple Sclerosis

open access: yesAnnals of Neurology, EarlyView.
Objective A better understanding of factors associated with multiple sclerosis (MS) disease activity and disability is needed. Given the strong link between comorbid depression and MS disease activity and disability, we aimed to determine whether the depression genetic burden, as modelled using its polygenic score, is associated with MS disease ...
Ali Manouchehrinia   +24 more
wiley   +1 more source

Comparative Safety Profiles of Ocrelizumab and Rituximab in Multiple Sclerosis Treatment Using Real‐World Evidence

open access: yesAnnals of Neurology, EarlyView.
Objective The objective of this study was to compare the long‐term safety profiles of ocrelizumab and rituximab in persons with multiple sclerosis (MS). Methods Using retrospective data from the University of California (UC) Health System, we simulated a target clinical trial. The primary cohort from UC San Francisco (UCSF) and a validation cohort from
Gabriel Cerono   +3 more
wiley   +1 more source

Random Dynamics and Finance: Constructing Implied Binomial Trees from a Predetermined Stationary Den [PDF]

open access: yes
We introduce a general binomial model for asset prices based on the concept of random maps. The asymptotic stationary distribution for such model is studied using techniques from dynamical systems.
Manuel Morales   +3 more
core  

The lower jaw of Devonian ray‐finned fishes (Actinopterygii): Anatomy, relationships, and functional morphology

open access: yesThe Anatomical Record, EarlyView.
Abstract Actinopterygii is a major extant vertebrate group, but limited data are available for its earliest members. Here we investigate the morphology of Devonian actinopterygians, focusing on the lower jaw. We use X‐ray computed tomography (XCT) to provide comprehensive descriptions of the mandibles of 19 species, which span the whole of the Devonian
Ben Igielman   +11 more
wiley   +1 more source

Identifying Predictive Biomarkers of Response in Patients With Rheumatoid Arthritis Treated With Adalimumab Using Machine Learning Analysis of Whole‐Blood Transcriptomics Data

open access: yesArthritis &Rheumatology, EarlyView.
Objective Tumornecrosis factor inhibitors (TNFi) have significantly improved rheumatoid arthritis (RA) management, yet variability in patient response remains a substantial challenge, with approximately 40% of patients discontinuing TNFi due to nonresponse or adverse effects.
Chuan Fu Yap   +12 more
wiley   +1 more source

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