Results 181 to 190 of about 389,511 (337)

Randomly sparsified Richardson iteration: A dimension‐independent sparse linear solver

open access: yesCommunications on Pure and Applied Mathematics, EarlyView.
Abstract Recently, a class of algorithms combining classical fixed‐point iterations with repeated random sparsification of approximate solution vectors has been successfully applied to eigenproblems with matrices as large as 10108×10108$10^{108} \times 10^{108}$. So far, a complete mathematical explanation for this success has proven elusive.
Jonathan Weare, Robert J. Webber
wiley   +1 more source

Integrated Population Pharmacokinetic, Pharmacodynamic, and Safety Analyses to Inform Dosage Selection in the Clinical Development of the ATR Inhibitor Tuvusertib

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
We present model‐informed selection of the recommended dose for expansion (RDE) of investigational oral ATR inhibitor tuvusertib, by integrating clinical pharmacokinetics (PK), pharmacodynamics (PD), and safety data from DDRiver Solid Tumors 301 trial Part A1 (NCT04170153).
Jatinder Kaur Mukker   +20 more
wiley   +1 more source

Signaling Sustainability, Inviting Scrutiny: How Sustainability Policies Shape the Focus of Shareholder Activism

open access: yesCorporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT This paper investigates whether and to what extent corporate sustainability policies attract shareholder activism—and whether such attention is general or selectively targeted. While sustainability initiatives are typically viewed as signals of legitimacy and ethical commitment, we argue that they may also heighten stakeholder expectations and
Maria Cristina Zaccone
wiley   +1 more source

Business Intelligence in Supply Chain Management: Insights for Performance and Sustainability

open access: yesCorporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT The increasing availability of digital technologies enables companies to manage large volumes of data and optimize their supply chains, with significant implications for both business performance and sustainability. While scholars have shown growing interest in the opportunities offered by Business Intelligence (BI) and Business Analytics (BA),
Fabio Caputo   +2 more
wiley   +1 more source

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