Results 41 to 50 of about 400,831 (325)

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

On approximation of Markov binomial distributions

open access: yes, 2009
For a Markov chain $\mathbf{X}=\{X_i,i=1,2,...,n\}$ with the state space $\{0,1\}$, the random variable $S:=\sum_{i=1}^nX_i$ is said to follow a Markov binomial distribution.
Xia, Aihua, Zhang, Mei
core   +2 more sources

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu   +10 more
wiley   +1 more source

Analyses of multiplicity distributions by means of the Modified Negative Binomial Distribution and its KNO scaling function [PDF]

open access: yes, 1997
We analyze various data of multiplicity distributions by means of the Modified Negative Binomial Distribution (MNBD) and its KNO scaling function, since this MNBD explains the oscillating behavior of the cumulant moment observed in e^+e^- annihilations ...
Biyajima, M.   +3 more
core   +2 more sources

Hip Morphology–Based Osteoarthritis Risk Prediction Models: Development and External Validation Using Individual Participant Data From the World COACH Consortium

open access: yesArthritis Care &Research, EarlyView.
Objective This study aims to develop hip morphology‐based radiographic hip osteoarthritis (RHOA) risk prediction models and investigates the added predictive value of hip morphology measurements and the generalizability to different populations. Methods We combined data from nine prospective cohort studies participating in the Worldwide Collaboration ...
Myrthe A. van den Berg   +26 more
wiley   +1 more source

Testing A Personalized Approach to Chronic Low Back Pain: A Randomized Controlled Trial in Older Veterans

open access: yesArthritis Care &Research, Accepted Article.
Objective We aimed to test the efficacy of personalized treatment of older Veterans with chronic low back pain (CLBP) delivered by Aging Back Clinics (ABC) as compared with usual care (UC). Methods Two hundred ninety‐nine Veterans age 65‐89 with CLBP from 3 VA medical centers underwent baseline testing, randomization to ABC or UC and 12 months follow ...
Debra K. Weiner   +9 more
wiley   +1 more source

MYCOPHENOLATE MOFETIL TREATMENT REDUCES THE RISK OF TREATMENT ESCALATION DUE TO VASCULAR COMPLICATIONS IN LIMITED CUTANEOUS SYSTEMIC SCLEROSIS: EMULATION OF A TARGET TRIAL FROM ITALIAN RHEUMATOLOGY SOCIETY SPRING REGISTRY

open access: yesArthritis Care &Research, Accepted Article.
Objective Mycophenolate Mofetil (MMF) use in limited cutaneous systemic sclerosis (lcSSc) is relatively uncommon due to the lower fibrotic burden and the predominance of the vascular complications. In vitro observations and clinical data from transplanted patients suggest a protective effect of MMF on endothelial function.
Enrico De Lorenzis   +77 more
wiley   +1 more source

A New Neutrosophic Negative Binomial Distribution: Properties and Applications

open access: yesJournal of Mathematics, 2021
Many problems in real life exist that are full of confusion, vagueness, and ambiguity. The quantification of such issues in a scientific way is the need of time.
Rehan Ahmad Khan Sherwani   +4 more
doaj   +1 more source

Nonextensive Statistics and Multiplicity Distribution in Hadronic Collisions

open access: yes, 2002
The multiplicity distribution of particles in relativistic gases is studied in terms of Tsallis' nonextensive statistics. For an entropic index q>1 the multiplicity distribution is wider than the Poisson distribution with the same average number of ...
Abe   +27 more
core   +1 more source

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