Results 41 to 50 of about 23,921,395 (244)
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Photocured room temperature phosphorescent materials from lignosulfonate
Nature CommunicationsPhotocured room temperature phosphorescent (RTP) materials hold great potential for practical applications but are scarcely reported. Here, we develop photocured RTP materials (P-Lig) using a combination of lignosulfonate, acrylamide, and ionic liquid (1-
Hongda Guo +9 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Epoxy resins are widely applied in various industries owing to its excellent comprehensive properties. Nevertheless, the manufacturing process of conventional epoxy resins is overdependent on petroleum resources, which is harmful to the environment ...
Ye, Guofeng, Huo, Guofeng, Liu, Zhitian
core +1 more source
iScience, 2020 Summary: Adhesive hydrogels containing catechol moieties have many important applications, but the fabrication of effective long-lasting adhesive hydrogels remains a challenge because of oxidative damage.
Daming Xiao +7 more
doaj +1 more source
Nature Communications, 2021 Self-healing materials strive to emulate curable and resilient biological tissue but their performance is often insufficient for commercial applications because self-healing and toughening are mutually exclusive properties.
Youngho Eom +8 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Room temperature phosphorescence from natural wood activated by external chloride anion treatment
Nature Communications, 2023 Producing afterglow room temperature phosphorescence (RTP) from natural sources is an attractive approach to sustainable RTP materials. However, converting natural resources to RTP materials often requires toxic reagents or complex processing.
Yingxiang Zhai +6 more
doaj +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source