Results 101 to 110 of about 4,761 (245)

Seismic geological characteristics and gas reservoir distribution of Changxing Formation biological bio-reef reservoir in the Longhuichang-Tieshan area, northeastern Sichuan Basin, China

Journal of Natural Gas Geoscience
This research aims to address the ambiguity surrounding the extent of development of Changxing Formation bio-reef reservoirs in the Longhuichang-Tieshan area of the northeastern Sichuan Basin, China, and to elucidate the relationship between these ...
Hu Zhao, Juncheng Yi, Hang Zhang, Rongrong Zhao, Jiewei Zhang, Jingyun Dai, Le Lü, Hongyi An   +7 more
doaj   +1 more source

Estimating Seasonal Behavior States from Bio-logging Sensor Data

, 2015
The seasonal timing of key, annual life history events is an important component of many species' ecology. Seasonal periods important to marine mammals often do not align well with typical labels (i.e., spring, summer, winter, fall). The timing of key life history events is well documented only for species found in accessible rookeries or breeding ...
London, Josh, Johnson, Devin, Conn, Paul, McClintock, Brett, Cameron, Michael, Boveng, Peter   +5 more
openaire   +1 more source

TSPYL5 Promotes Triple‐Negative Breast Cancer Metastasis by Antagonizing USP10‐Mediated PTEN Stabilization to Unleash a ZEB1‐Dependent EMT Program

Advanced Science, EarlyView.
The hyperactivation of PI3K/AKT signaling in PTEN wild‐type triple‐negative breast cancer represents a clinical paradox. We delineate a novel post‐translational regulatory axis wherein the oncogene TSPYL5 competitively antagonizes the deubiquitinase USP10.
Jiaying Shi, Ming Yi, Shengyu Xie, Zhaokun Wang, Xinyue Zhang, Yangwei Zhang, Rui Tang, Yuan Yang, Yunqiang Liu   +8 more
wiley   +1 more source

Redox‐Dependent Chaperoning of GBF1 Condensates Regulates Seed Germination in Arabidopsis

Advanced Science, EarlyView.
In dormant seeds (low ROS), GBF1 forms liquid condensates to repress the germination gene CathB3, and the chaperone GIP1 maintains condensate liquidity and repressive activity. Upon imbibition (high ROS), ROS oxidize GIP1 during germination, impairing its chaperone function.
Yunying Wang, Xiaofeng Fang
wiley   +1 more source

Establishing bio-logging data collections as dynamic archives of animal life on Earth

Nature Ecology & Evolution
Rapid growth in bio-logging-the use of animal-borne electronic tags to document the movements, behaviour, physiology and environments of wildlife-offers opportunities to mitigate biodiversity threats and expand digital natural history archives. Here we present a vision to achieve such benefits by accounting for the heterogeneity inherent to bio-logging
Sarah C. Davidson, Francesca Cagnacci, Peggy Newman, Holger Dettki, Ferdinando Urbano, Peter Desmet, Lenore Bajona, Edmund Bryant, Ana P. B. Carneiro, Maria P. Dias, Ei Fujioka, David Gambin, Xavier Hoenner, Colin Hunter, Akiko Kato, Connie Y. Kot, Bart Kranstauber, Chi Hin Lam, Denis Lepage, Hemal Naik, Jonathan D. Pye, Ana M. M. Sequeira, Vardis M. Tsontos, Emiel van Loon, Danny Vo, Christian Rutz   +25 more
openaire   +8 more sources

Iron‐Mediated Release of Aged Dissolved Organic Carbon From Waterlogged Peatland Under Warming

Advanced Science, EarlyView.
This study conducts a five‐year in situ warming experiment in high‐altitude peatlands to examine dissolved organic carbon (DOC) release. The study shows that warming promotes the release of plant‐derived modern DOC in drained peatlands, but amplifies aquatic export of century‐old DOC from waterlogged peatlands via Fe‐mediated DOC mobilization—a ...
Guohua Dai, Zhiying Yang, Zongguang Liu, Wanjia Hu, Lixiao Ma, Enze Kang, Wanqing Luo, Yunpeng Zhao, Chengzhu Liu, Juan Jia, Ting Liu, Chen He, Quan Shi, Jianliang Liu, Yongheng Gao, Huai Chen, Hailong Zhang, Meixun Zhao, Xiaojuan Feng   +18 more
wiley   +1 more source

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

The New Era of Physio-Logging and Their Grand Challenges

Frontiers in Physiology, 2021
Andreas Fahlman, Kagari Aoki, Gemma Bale, Jeroen Brijs, Ki H. Chon, Colin K. Drummond, Martin Føre, Xavier Manteca, Birgitte I. McDonald, J. Chris McKnight, Kentaro Q. Sakamoto, Ippei Suzuki, M. Jordana Rivero, Yan Ropert-Coudert, Danuta M. Wisniewska   +14 more
doaj   +1 more source

Integrative Multi‐Omics Analysis Reveals a Mitochondrial–Immune Axis Associated With Neoadjuvant Chemotherapy Response in High‐Grade Serous Ovarian Cancer

Advanced Science, EarlyView.
Integrative multi‐omics analysis delineates a mitochondrial–immune axis governing neoadjuvant chemotherapy response in high‐grade serous ovarian cancer. Immune‐active tumors exhibit enhanced B‐cell infiltration and favorable sensitivity, whereas metabolically rewired tumors display oxidative phosphorylation dependency and resistance.
Wei Jiang, Yi Wang, Xiaohang Lu, Qianlan Yao, Libing Xiang, Xu Cai, Xiaoyu Tu, Shaoxian Tang, Ying Xu, Yufan Cheng, Liming Shen, Huijuan Yang   +11 more
wiley   +1 more source

Harnessing MDM2‐Mediated Targeted Degradation of Transcriptional and Epigenetic Machinery to Disrupt Oncogenic Addictions in Pediatric Sarcoma

Advanced Science, EarlyView.
MDM2 dependency in pediatric sarcomas is driven by a novel p53‐independent oncogenic cistrome alongside canonical p53 pathway suppression. This study introduces MDM2‐recruiting transcriptional and epigenetic machinery degraders (MDM2‐TEMADs) as a novel precision oncology modality.
Jiawei Zhou, Xian Guan, Nan Li, Ying Zhang, Long Xie, Xingze Huang, Zhipeng Zhu, Zhuolin Ren, Xiaoyan Yu, Hanjun Guo, Yuanfang Wu, Lin Ma, Suya Zheng, Jingyao Zhang, Jiyang Liu, Victor Kuanmin Lee, Wenhao Chen, H. Phillip Koeffler, Jinhu Wang, Xin Han, Ye Chen, Liang Xu   +21 more
wiley   +1 more source