Results 231 to 240 of about 6,578 (291)

Computational Cellular Mathematical Model Aids Understanding the cGAS-STING in NSCLC Pathogenicity. [PDF]

Bio Protoc
Khandibharad S, Gulhane P, Singh S.
europepmc   +1 more source

Ultrastrong TEMPO‐Oxidized Densified Bamboo via Interface Decoupling and Hierarchical Toughening

Advanced Science, EarlyView.
This study develops TEMPO‐oxidized densified bamboo that achieves ultrahigh strength and toughness by decoupling rigid hydrogen bonds into reversible van der Waals interactions. TEMPO oxidation reorganizes the cellulose hydrogen‐bonding network, facilitating energy dissipation via reversible interactions, thereby establishing a general strategy to ...
Ziyu Ba, Hongyun Luo, Jie Cui, Juan Guan, Zhaoliang Guo, Robert O. Ritchie   +5 more
wiley   +1 more source

Low-Power IMU System for Attitude Estimation-Based Plastic Greenhouse Foundation Uplift Monitoring. [PDF]

Sensors (Basel)
Park G, Park J, Jung E, Lee J, Hwang H, Song J, Yu S, Lim S, Park J.   +8 more
europepmc   +1 more source

Cryoablation Activates the cGAS–STING‐CXCL10 Axis in Macrophages to Enhance Anti‐Tumor Immunity in NSCLC

Advanced Science, EarlyView.
Tumor dsDNA released by cryoablation is taken up by macrophages, activating the cGAS‐STING signaling pathway. This leads to an expansion of the CXCL10+ macrophage pool and increased secretion of CXCL10, which in turn recruits CXCR3+ T cells from draining lymph nodes into the tumor microenvironment to exert anti‐tumor effects.
Xinxin Zhi, Zhengcao Xing, Libo Luo, Jiale Wang, Xinyu Liu, Jia Yu, Jizhong Yin, Bin Chen, Yiwei Liu, Hui Sun, Guanghui Gao, Lei Wang, Xiaoxia Chen, Fei Li, Hu Ma, Lin Wang, Shuo Yang, Shengxiang Ren   +17 more
wiley   +1 more source

Bird migration on the edge: Experimental manipulation of corticosterone advances departure dates. [PDF]

Ecology
Hoarau M, Dulude-de Broin F, LeTourneux F, Angelier F, Gauthier-Bouchard M, Martin MC, Kato A, Lefebvre J, Thomas PJ, Williams CK, Bêty J, Legagneux P.   +11 more
europepmc   +1 more source

Selective Inhibition of Integrin β3 Topology Provides a Safer Antithrombotic Strategy

Advanced Science, EarlyView.
Current integrin αIIbβ3 inhibitors effectively reduce thrombosis but also increase bleeding risk. During thrombosis, high shear blood flow can directly activate the integrin αIIbβ3 via a distinct topological change in the β3 transmembrane domain, independent of hemostatic platelet signaling.
Joonha Lee, Chul‐Gyun Lim, Pothiappan Vairaprakash, Jong‐Min Kim, Jiyoon Kim, Ji‐Young Park, Klaus M. Hahn, Hyunbo Shim, Hae Woong Choi, Tobias S. Ulmer, Soon Jun Hong, Chungho Kim   +11 more
wiley   +1 more source

Cost analysis for the implementation of LUCF mitigation toward NDC target in Indonesia. [PDF]

Carbon Balance Manag
Rossita A, Boer R.
europepmc   +1 more source

POU2F1 Promotes Chemoresistance in Colorectal Cancer Cells via Attenuates the MDR2 Degradation Mediated by PPP1R11 Lactylation

Advanced Science, EarlyView.
Schematic diagram of our study showing that highly expressed POU2F1 in colorectal cancer (CRC) can directly accelerate the cytosolic lactate export to decrease PPP1R11 lactylation at K59, thereby attenuating the E3 ligase enzyme activity and protein stability of PPP1R11, which inhibits the ubiquitination of MDR2 at K413 and K538 but increases the ...
Longzheng Xia, Jinguan Lin, Xianjie Jiang, Linda Oyang, Shiming Tan, Zongyao Ren, Qiu Peng, Qianjin Liao, Yujuan Zhou   +8 more
wiley   +1 more source

Resilience Challenges in Bioeconomy Policies: A Global Comparative Analysis. [PDF]

Environ Manage
Goritz N, Proestou M, Feindt PH.
europepmc   +1 more source

ALKBH3 m1A Demethylase Deficiency Reduces Alzheimer's Amyloid‐β Pathology

Advanced Science, EarlyView.
This study identifies that ALKBH3‐driven m1A demethylation orchestrates Alzheimer's disease progression by disrupting mitochondrial and synaptic homeostasis. This epitranscriptomic mechanism suppresses PINK1‐mediated mitophagy via m1A erasure, leading to mitochondrial dysfunction, oxidative stress, elevated Aβ production, and impaired microglial ...
Yueyang Li, Sifei Yu, Kaidong Lu, Yujie Zhang, Mingjie Dong, Yan Peng, Liang Xue, Waleed Alam, Yuxuan Shui, Yi Zhou, Wuyunhan Ma, Meng Bao, Peiming Li, Peiyi Luo, Tiezhan Lu, Jiajia Li, Kang Zhang, Yuying Wang, Shuchen Yang, Nuoya Yin, Francesco Faiola, Zilong Gao, Jingfeng Zhou, Fei Zhao, Yali He, Magdalena J. Koziol   +25 more
wiley   +1 more source