Results 91 to 100 of about 1,200,876 (308)

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Bio-Medical Library Bulletin, No. 19 (1971-03)

open access: yes, 1971
Bio-Medical Library. (1971). Bio-Medical Library Bulletin, No. 19 (1971-03).
Bio-Medical Library
core  

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

open access: yesFEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Bio-Medical Library Bulletin, No. 99 (1988-11)

open access: yes, 1988
Bio-Medical Library. (1988). Bio-Medical Library Bulletin, No. 99 (1988-11).
Bio-Medical Library
core  

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

Bio-Medical Library Bulletin, No. 91 (1986-10)

open access: yes, 1986
Bio-Medical Library. (1986). Bio-Medical Library Bulletin, No. 91 (1986-10).
Bio-Medical Library
core  

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

Bio-waste Crude Extracts as Alternatives to Synthetic Antioxidants in Petroleum Lubricants

open access: yesEthiopian Journal of Science and Sustainable Development
The increasing environmental concerns and the need for enhanced lubricant stability in petroleum industry necessitate sustainable solutions. This paper reports the use of crude extracts from bio-wastes of lemongrass and pepper fruits, as eco-friendly ...
Ramla L. Nassoro   +3 more
doaj   +1 more source

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