Results 91 to 100 of about 193,280 (312)

Correlation between Bioassay and Protein Misfolding Cyclic Amplification for Variant Creutzfeldt-Jakob Disease Decontamination Studies

mSphere, 2020
To date, approximately 500 iatrogenic Creutzfeldt-Jakob disease cases have been reported worldwide, most of them resulting from cadaveric dura mater graft and from the administration of prion-contaminated human growth hormone.
Maxime Bélondrade, Christelle Jas-Duval, Simon Nicot, Lilian Bruyère-Ostells, Charly Mayran, Laetitia Herzog, Fabienne Reine, Juan Maria Torres, Chantal Fournier-Wirth, Vincent Béringue, Sylvain Lehmann, Daisy Bougard   +11 more
doaj   +1 more source

Evaluation of the Long-Lasting Insecticidal Net Interceptor LN: Laboratory and Experimental Hut Studies against Anopheline and Culicine Mosquitoes in Northeastern Tanzania [PDF]

, 2013
Long lasting insecticidal nets (LN) are a primary method of malaria prevention. Before new types of LN are approved they need to meet quality and efficacy standards set by the WHO Pesticide Evaluation Scheme.
Caroline Maxwell, Harparkash Kaur, Malima, Robert, Mark Rowland, Matthew J Kirby, Patrick K Tungu, Robert Malima, Stephen M Magesa, Victor Mwingira   +8 more
core   +3 more sources

Pharmacological evaluation of Adenostemma lavenia acetone extract in Swiss Albino mice: Analgesic, anti‐inflammatory, and thrombolytic insights from in vivo, in vitro, density functional theory, and molecular docking studies

Animal Models and Experimental Medicine, EarlyView.
Adenostemma lavenia, a traditionally used medicinal plant, has been employed to manage pain, inflammation, and circulatory issues. This study investigates the analgesic, anti‐inflammatory, and thrombolytic potentials of the acetone extract of A. lavenia leaves (AEAL) using in vivo, in vitro, and in silico methods.
Nusrat Jahan Moon, Mahathir Mohammad, Md. Jahirul Islam Mamun, Fahmina Binty Azim Nova, Nazmul Hasan Eshaque, Md. Hossain Rasel, Zobayed Islam, Md. Mahmudul Hasan, Md. Liakot Ali, Md. Tanvir Chowdhury, S. M. Moazzem Hossen   +10 more
wiley   +1 more source

Outlining the Potential Role of Humic Products in Modifying Biological Properties of the Soil—A Review

Frontiers in Environmental Science, 2019
There is a growing awareness among farmers about the importance of soil for sustaining crop production and soil health. Marked interests in “environmentally-friendly” soil fertilization in agriculture has attracted significant attention in the last ...
Maria Pukalchik, Kamila Kydralieva, Kamila Kydralieva, Olga Yakimenko, Elena Fedoseeva, Elena Fedoseeva, Vera Terekhova, Vera Terekhova   +7 more
doaj   +1 more source

Bioassay Analysis Using R [PDF]

We describe an add-on package for the language and environment R which allows simultaneous fitting of several non-linear regression models. The focus is on analysis of dose response curves, but the functionality is applicable to arbitrary non-linear ...
Christian Ritz, Jens C. Streibig
core   +1 more source

Oxytocin‐ und Vasopressin‐Photosonden zur Entschlüsselung der Neuropeptid‐Signalgebung mit hoher räumlicher und zeitlicher Präzision

Angewandte Chemie, EarlyView.
Neue biokompatible Oxytocin‐ und Vasopressin‐Photosonden mit modernsten Photocages. Diese Photosonden sind inaktiv und können mit spezifischen Lichtwellen entschützt werden, was eine Rezeptoraktivierung mit hoher zeitlicher und räumlicher Kontrolle ermöglicht. Abbildung erstellt mit https://BioRender.com ZUSAMMENFASSUNG Das Oxytocin/Vasopressin (OT/VP)
Konstantin Raabe, Predrag Kalaba, Xuan Ling Hilary Yong, Greta Crudeli, Sarah Melzer, Erik Keimpema, Victor Anggono, Markus Muttenthaler   +7 more
wiley   +1 more source

Antiproliferation, 3D-multicellular spheroid and VEGFR-2 inhibitory properties of spiroindolin-2-ones with phosphonate function

Scientific Reports
Spiroindolin-2-ones with phosphonate function 17a‒t (20 analogs, 96‒72% yield) were generated by microwave synthetic methodology using azomethine cycloaddition of the appropriate 3,5-bis(ylidene)-4-piperidone-1-phosphonate 14a‒g.
Sara M. Hassan, Alyaa Farid, Mohamed S. Bekheit, Siva S. Panda, Benson M. Kariuki, Anwar Abdelnaser, Soad Nasr, Walid Fayad, May A. El-Manawaty, Ahmed A. F. Soliman, Adel S. Girgis   +10 more
doaj   +1 more source

A Cell-Based Potency Assay for Determining the Relative Potency of Botulinum Neurotoxin A Preparations Using Manual and Semi-Automated Procedures

Toxins
Cell-based potency assays (CBPAs) are required for the potency testing and commercial release of botulinum neurotoxin (BoNT)-based drug products. These CBPAs must account for the toxin’s biological activities while meeting regulatory guidelines for ...
F. Mark Dunning, Sara Hendrickson, Serena Wolfe, Dan Harding, Theresa Geurs, Timothy M. Piazza, Thomas A. Little, Ward C. Tucker   +7 more
doaj   +1 more source

Bioassay-guided isolation and identification of antimicrobial compounds from thyme essential oil by means of overpressured layer chromatography, bioautography and GC-MS [PDF]

, 2012
A simple method is described for efficient isolation of compounds having an antibacterial effect. Two thyme (Thymus vulgaris) essential oils, obtained from the market, were chosen as prospective materials likely to feature several bioactive components ...
Andrea Böszörményi, B Lorber, BJ Juven, C Anagnostopoulos, C Rota, E Mincsovics, E Mincsovics, E Mincsovics, E Wedge, Emil Mincsovics, EO King, Ernő Tyihák, Gy Horváth, IM Choma, J Fan, L Botz, PZ Wang, Péter G. Ott, RR Nelson, S Koduru, Ágnes M. Móricz, ÁM Móricz, ÁM Móricz, Éva Lemberkovics   +23 more
core   +1 more source

Photocaged Oxytocin and Vasopressin Probes to Decipher Neuropeptide Signalling With High Spatiotemporal Resolution

Angewandte Chemie International Edition, EarlyView.
Novel and biocompatible photoactivatable oxytocin and vasopressin probes, utilising state‐of‐the‐art photocages, remain inactive in the dark. Light exposure facilitates rapid spatiotemporal receptor activation and phospholipase C (PLC)‐mediated downstream signalling. Figure created in https://BioRender.com.
Konstantin Raabe, Predrag Kalaba, Xuan Ling Hilary Yong, Greta Crudeli, Sarah Melzer, Erik Keimpema, Victor Anggono, Markus Muttenthaler   +7 more
wiley   +1 more source