Results 121 to 130 of about 296,429 (339)

Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT)

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons, Marc A. Beal, Kerry L. Dearfield, George R. Douglas, Min Gi, B. Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Michelle Kenyon, Alexandra S. Long, David P. Lovell, Anthony M. Lynch, Meagan B. Myers, Stefan Pfuhler, Alisa Vespa, Andreas Zeller, George E. Johnson, Paul A. White   +17 more
wiley   +1 more source

Comportamento de herbicidas com efeito residual em diferentes coberturas na cultura do feijoeiro Performance of residual herbicides applied in pre planting in dry bean crop

Planta Daninha, 2004
O objetivo deste trabalho foi avaliar o comportamento de herbicidas com efeito residual em diferentes tipos de cobertura vegetal no sistema plantio direto, antes da semeadura do feijoeiro.
T. Cobucci, C.M.O. Portela, W. Silva, A. Neto Monteiro   +3 more
doaj   +1 more source

In vitro effects of three woody plant and sainfoin extracts on two parasitic stage of 3 parasitic nematode species [PDF]

, 2004
Most studies on the effects of tanniferous plants on nematodes have examined forages but have neglected the woody plants. Therefore, in vitro effects of extracts from 3 woody plants (Rubus fructicosus, Quercus robur, Corylus avellana) have been tested on
H., HOSTE, I., FOURASTE, V., PAOLINI
core  

In vitro effect of canine hyperimmune sera on TNFa activity [PDF]

, 2006
[Introduction]: Septic shock in dogs is caused by cardiovascular and vasomotor failure associated with an uncontrolled intrinsic release of inflammatory mediators [1–5].
Kotiw, Michael, Reeve-Johnson, Lloyd, Shiels, I. A., Wilson, R. P.   +3 more
core   +2 more sources

A Vesicular Stomatitis Virus Replicon-Based Bioassay for the Rapid and Sensitive Determination of Multi-Species Type I Interferon

PLoS ONE, 2011
Type I interferons (IFN) comprise a family of cytokines that signal through a common cellular receptor to induce a plethora of genes with antiviral and other activities. Recombinant IFNs are used for the treatment of hepatitis C virus infection, multiple
Marianne Berger Rentsch, G. Zimmer
semanticscholar   +1 more source

Epigenotoxicity: Decoding the epigenetic imprints of genotoxic agents and their implications for regulatory genetic toxicology

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Regulatory genetic toxicology focuses on DNA damage and subsequent gene mutations. However, genotoxic agents can also affect epigenetic marks, and incorporation of epigenetic data into the regulatory framework may thus enhance the accuracy of risk assessment.
Roger Godschalk, Christopher Faulk, Jessica LaRocca, Jan van Benthem, Francesco Marchetti   +4 more
wiley   +1 more source

Mobilidade do ametryn em solos da região semiárida do Rio Grande do Norte Ametryn mobility in soils of Rio Grande do Norte semiarid region

Planta Daninha, 2012
Objetivou-se com este trabalho avaliar o potencial de mobilidade do ametryn em quatro tipos de solos: três da região semiárida do Estado do Rio Grande do Norte (Cambissolo, Neossolo Flúvico e Argissolo Vermelho-Amarelo distrófico latossólico) e um do ...
F.C.L. Freitas, A.A. Silva, L.O.C. Silva, P.R.R. Rocha, F.C.N. Guimarães, M.A.M. Freitas, R. S. Felipe   +6 more
doaj   +1 more source

Mikroorganismen an Aesculus hippocastanum – olfaktorische Perspektive von Cameraria ohridella (Deschka & Dimic) [PDF]

, 2008
Since the 80s, the popular park- and city tree Aesculus hippocastanum has been infested with the leaf miner Cameraria ohridella (DESCHKA & DIMIC 1986). Additionally, the pathogenic fungi Guignardia aesculi causes leaf blotch disease and Erysiphe flexuosa
Johne, A. Bettina, Schütz, Stefan, Weißbecker, Bernhard   +2 more
core  

Consensus findings of an International Workshops on Genotoxicity Testing workshop on using transcriptomic biomarkers to predict genotoxicity

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Gene expression biomarkers have the potential to identify genotoxic and non‐genotoxic carcinogens, providing opportunities for integrated testing and reducing animal use. In August 2022, an International Workshops on Genotoxicity Testing (IWGT) workshop was held to critically review current methods to identify genotoxicants using ...
Roland Froetschl, J. Christopher Corton, Henghong Li, Jiri Aubrecht, Scott S. Auerbach, Florian Caiment, Tatyana Y. Doktorova, Yurika Fujita, Danyel Jennen, Naoki Koyama, Matthew J. Meier, Roman Mezencev, Leslie Recio, Takayoshi Suzuki, Carole L. Yauk   +14 more
wiley   +1 more source

Cytotoxicity of 19 Pesticides in Rainbow Trout Gill, Liver, and Intestinal Cell Lines

Environmental Toxicology and Chemistry, EarlyView.
Abstract The rainbow trout gill cell line (RTgill‐W1), via test guideline 249 of the Organisation for Economic Co‐operation and Development, has been established as a promising New Approach Methodology, although to advance confidence in the method more case studies are needed that: 1) expand our understanding of applicability domains (chemicals with ...
Sophie Emberley‐Korkmaz, Krittika Mittal, Na'im Temlock, Jessica Head, Niladri Basu   +4 more
wiley   +1 more source