Results 141 to 150 of about 75,580 (245)

Is the presence of estradiol benzoate in cow feces environmentally safe? [PDF]

open access: yesEnviron Monit Assess
Guidoni LLC   +9 more
europepmc   +1 more source

Spectral response of guava leaves under infestation by Costalimaita ferruginea (coleoptera: Chrysomelidae)

open access: yesAgricultural and Forest Entomology, EarlyView.
Coccinellidae (Coleoptera), Miridae (Hemiptera), Hemerobiidae (Neuroptera), Pentatomidae (Hemiptera), Anystidae (Acari), Erythraeidae (Acari) and spiders (Araneidae, Oxyopidae and Salticidae) fed on the invasive paropsine leaf beetles in Marlborough, New Zealand.
Souradji I. Bachirou   +2 more
wiley   +1 more source

Measuring Propidium Iodide Brightness as a Function of Viability: A High‐Throughput Quantitative Assessment of Hepatic Spheroids

open access: yesArtificial Organs, EarlyView.
The graphical abstract illustrates our rapid PI‐based spheroid viability assay: hepatocyte spheroids are formed and stained with AO/PI, imaged after a 15‐min incubation, and analyzed for PI brightness normalized to area. This metric correlates strongly with functional urea/DNA output, validating PI intensity as a fast, reliable indicator of spheroid ...
Michael G. Megaly   +11 more
wiley   +1 more source

Assay2Mol: Large Language Model-based Drug Design Using BioAssay Context. [PDF]

open access: yesProc Conf Empir Methods Nat Lang Process
Deng Y, Ericksen SS, Gitter A.
europepmc   +1 more source

Rapid generation of prion disease models using AAV‐delivered PrP variants in knockout mice

open access: yesBrain Pathology, EarlyView.
We developed a rapid AAV‐based system to generate prion disease models in weeks rather than months. Following systemic AAV9P31 delivery of modified PrP to knockout mice, we achieved brain‐wide expression and successful propagation of both classical (RML) and atypical (GSS‐A117V) prion strains.
Maitena San‐Juan‐Ansoleaga   +11 more
wiley   +1 more source

Synthesis of <i>Arapaima gigas</i> Growth Hormone (ag-GH) in HEK 293 Cells: Its Purification and Characterization via In Vivo Bioassay in Dwarf "Little" Mice. [PDF]

open access: yesMolecules
Lima ER   +11 more
europepmc   +1 more source

The L108I polymorphism in mouse prion protein drives spontaneous disease and enhances transmission of atypical and classical prion strains

open access: yesBrain Pathology, EarlyView.
A single amino acid change (L108I) combined with PrP overexpression drives spontaneous atypical prion formation in mice, enabling also efficient propagation of diverse prion strains. This model allows studying how spontaneous prion diseases arise and provides powerful tools for investigating strain emergence, transmission barriers, and mechanisms ...
Hasier Eraña   +20 more
wiley   +1 more source

Comprehensive transduceromic profiling of NOP receptor ligands at different Gα subunits

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose The nociceptin/orphanin FQ (N/OFQ) peptide receptor (NOP) is an opioid receptor family member with distinct pharmacology and broad therapeutic potential. NOP receptors regulate functions such as nociception, stress reactivity, reward, mood, autonomic tone, immunity and sleep/wake cycle.
Davide Malfacini   +9 more
wiley   +1 more source

Integrating artificial intelligence and manual curation to enhance bioassay annotations in ChEMBL. [PDF]

open access: yesJ Cheminform
Smit I   +8 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy