ChEMBL: towards direct deposition of bioassay data
ChEMBL is a large, open-access bioactivity database (https://www.ebi.ac.uk/chembl), previously described in the 2012, 2014 and 2017 Nucleic Acids Research Database Issues.
David Mendez +20 more
semanticscholar +1 more source
Evidence of the indirect hormonal activity of prohormones using liver S9 metabolic bioactivation and an androgen bioassay [PDF]
Prohormones such as dehydroepiandrosterone (DHEA) are steroid precursors that do not show hormonal activity by themselves. Abuse of these prohormones in cattle fattening is hard to prove because of strong in vivo metabolism and the difficulty to detect ...
Bovee, T.F.H. +4 more
core +2 more sources
EFFICACY AND BIOCHEMICAL EFFECTS OF SOME INSECTICIDES AGAINST COTTON LEAFWORM, Spodoptera littoralis (BOISD.) [PDF]
he efficiency and biochemical effects of certain insecticides belonging to different groups namely: flubendiamide (diamide), pyridalyl (phenoxy-pyridaloxy), clothianidin (neonicotinoide), fipronil (phenylpyrazole) and spirotetramat (tetramic acid) and ...
Rasha Sleem +3 more
doaj +1 more source
Management of plant health risks associated with processing of plant-based wastes: A review [PDF]
The rise in international trade of plants and plant products has increased the risk of introduction and spread of plant pathogens and pests. In addition, new risks are arising from the implementation of more environmentally friendly methods of ...
Budge, G. E. +4 more
core +1 more source
Monitoring resistance of Cydia pomonella (L.) Spanish field populations to new chemical insecticides and the mechanisms involved [PDF]
BACKGROUND: A widespread resistance of Cydia pomonella to organophosphates was demonstrated in populations from the Spanish Ebro Valley area that showed high levels of enzymatic detoxification.
Avilla Hernández, Jesús +2 more
core +3 more sources
Oviposition by the Banded Sunflower Moth, \u3ci\u3eCochylis Hospes\u3c/i\u3e (Lepidoptera: Cochylidae) in Response to \u3ci\u3eHelianthus Annuus\u3c/i\u3e Pollen [PDF]
Oviposition on an artificial substrate by the banded sunflower moth Cochylis hospes Walsingham was examined in response to sunflower pollen (Helianthus annuus) and sunflower pollen extract.
Barker, John F, Grugel, Sharon
core +2 more sources
HIV-positive nigerian adults harbor significantly higher serum lumefantrine levels than HIV-negative individuals seven days after treatment for Plasmodium falciparum infection. [PDF]
Management of coinfection with malaria and HIV is a major challenge to public health in developing countries, and yet potential drug-drug interactions between antimalarial and antiviral regimens have not been adequately investigated in people with both ...
Albert van Wyk +30 more
core +1 more source
PubChem's BioAssay database (https://pubchem.ncbi.nlm.nih.gov) has served as a public repository for small-molecule and RNAi screening data since 2004 providing open access of its data content to the community.
Yanli Wang +8 more
semanticscholar +1 more source
A series of 1″-(alkylsulfonyl)-dispiro[indoline-3,2′-pyrrolidine-3′,3″-piperidine]-2,4″-diones 6a‒o has been synthesized through regioselective multi-component azomethine dipolar cycloaddition reaction of 1-(alkylsulfonyl)-3,5-bis(ylidene)-piperidin-4 ...
Nehmedo G. Fawazy +13 more
doaj +1 more source
No evidence for a culturable bacterial tetrodotoxin producer in Pleurobranchaea maculata (Gastropoda: Pleurobranchidae) and Stylochoplana sp. (Platyhelminthes: Polycladida) [PDF]
Tetrodotoxin (TTX) is a potent neurotoxin found in the tissues of many taxonomically diverse organisms. Its origin has been the topic of much debate, with suggestions including endogenous production, acquisition through diet, and symbiotic bacterial ...
Cary, S. Craig +3 more
core +3 more sources

