Results 211 to 220 of about 78,928 (266)
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Endocrinology, 1953
IN 1926 Hisaw first demonstrated experimentally the relaxation of the pelvic ligaments of guinea pigs during estrus following the injection of blood serum from pregnant rabbits. Later work indicated a specific hormone, designated as relaxin, was responsible for the looseness of the symphysis pubis, since the effect was also observed following injection
R I, DORFMAN +2 more
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IN 1926 Hisaw first demonstrated experimentally the relaxation of the pelvic ligaments of guinea pigs during estrus following the injection of blood serum from pregnant rabbits. Later work indicated a specific hormone, designated as relaxin, was responsible for the looseness of the symphysis pubis, since the effect was also observed following injection
R I, DORFMAN +2 more
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Biometrics, 1980
In a multivariate bioassay the response variable is r-dimensional and the dose variable is one-dimensional. Thus, the graph of the dose response relation is a curve in the (r+1)-dimensional space. The similarity requirement for a test and a standard is divided into two parts: (i) a condition of marginal similarity corresponding to the usual similarity ...
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In a multivariate bioassay the response variable is r-dimensional and the dose variable is one-dimensional. Thus, the graph of the dose response relation is a curve in the (r+1)-dimensional space. The similarity requirement for a test and a standard is divided into two parts: (i) a condition of marginal similarity corresponding to the usual similarity ...
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Theoretical Population Biology, 1971
Abstract Kinship between two population I and J , defined as the probability of identity by descent for a random pair of alleles from I and J , can be estimated by bioassay of phenotypes, names, metrics, and gene frequencies, and can be predicted from genealogy and demography by both deterministic and Monte Carlo methods.
N E, Morton, S, Yee, D E, Harris, R, Lew
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Abstract Kinship between two population I and J , defined as the probability of identity by descent for a random pair of alleles from I and J , can be estimated by bioassay of phenotypes, names, metrics, and gene frequencies, and can be predicted from genealogy and demography by both deterministic and Monte Carlo methods.
N E, Morton, S, Yee, D E, Harris, R, Lew
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Multivariate Bioassay, Combination of Bioassays, and Fieller's Theorem
Biometrics, 1986In this paper alternative methods for estimating the relative potency, its confidence intervals, and testing for proportionality are developed for multivariate bioassays. The test and estimate are based on the smaller characteristic root and the corresponding characteristic vector of a 2 X 2 matrix.
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Human Pathology, 1984
Bioassay of hormones has a small but important role in defining the physiologic status of selected patients in whom immunoassay results do not correlate with clinical signs and symptoms. This article reviews three sensitive bioassays for hormones, which are based on 1) stimulation of adenylate cyclase in membrane preparations, 2) cytochemical changes ...
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Bioassay of hormones has a small but important role in defining the physiologic status of selected patients in whom immunoassay results do not correlate with clinical signs and symptoms. This article reviews three sensitive bioassays for hormones, which are based on 1) stimulation of adenylate cyclase in membrane preparations, 2) cytochemical changes ...
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Controlled Clinical Trials, 1984
Linear multivariate theory is applied to \textit{A. Vølund}'s [ibid. 36, 225-236 (1980; Zbl 0436.62092)] multivariate bioassay problems resulting in more powerful tests of hypotheses, a simple ML estimator of relative potency, and a Fieller-like confidence interval.
Eugene M. Laska +3 more
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Linear multivariate theory is applied to \textit{A. Vølund}'s [ibid. 36, 225-236 (1980; Zbl 0436.62092)] multivariate bioassay problems resulting in more powerful tests of hypotheses, a simple ML estimator of relative potency, and a Fieller-like confidence interval.
Eugene M. Laska +3 more
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Planta, 1966
A bioassay is described which is dependent upon the fact that gibberellin induced α-amylase release from barley half-seeds is proportional to the logarithm of gibberellin concentration applied. This bioassay has been successfully applied to the estimation of gibberellin-like substances in plant extracts.
R L, Jones, J E, Varner
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A bioassay is described which is dependent upon the fact that gibberellin induced α-amylase release from barley half-seeds is proportional to the logarithm of gibberellin concentration applied. This bioassay has been successfully applied to the estimation of gibberellin-like substances in plant extracts.
R L, Jones, J E, Varner
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2003
Cytokines are important mediators in inflammation, and play a key role in inflammation induced by Gram-negative bacteria. Cytokines are released into serum during different pathological conditions, such as meningococcal disease, and the cytokine levels in serum seem to correlate with fatal outcome of septic shock (1-3).
N B, Liabakk +4 more
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Cytokines are important mediators in inflammation, and play a key role in inflammation induced by Gram-negative bacteria. Cytokines are released into serum during different pathological conditions, such as meningococcal disease, and the cytokine levels in serum seem to correlate with fatal outcome of septic shock (1-3).
N B, Liabakk +4 more
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Combining Multivariate Bioassays
Biometrics, 1986Linear multivariate theory is applied to the problem of combining several multivariate bioassays. Results are an asymptotic test of the hypothesis of a common log relative potency; the maximum likelihood estimator of the common log relative potency; and an exact and asymptotic confidence interval estimator for log relative potency.
Meisner, Morris +2 more
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Biometrics, 1965
The generally accepted practices of biological assay, at least in so far as these are concerned with quantitative estimation, are contained within the concept of dilution assays (Finney [1964]; Jerne and Wood [1949]). In an analytical assay, each test preparation is regarded as a dilution of the standard preparation with a totally inert diluent.
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The generally accepted practices of biological assay, at least in so far as these are concerned with quantitative estimation, are contained within the concept of dilution assays (Finney [1964]; Jerne and Wood [1949]). In an analytical assay, each test preparation is regarded as a dilution of the standard preparation with a totally inert diluent.
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